Protein detail
F210B
Protein FAM210B, mitochondrial
Entry name F210B | UniProt ID | EVMP confidence score 0.50 |
Supporting publications (n) 3 | Transmembrane count 2 | Protein classification Predicted intracellular proteinsPredicted membrane proteins |
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40Basic Information13
Protein Names
Protein FAM210B, mitochondrial
Protein Class (2)
Predicted intracellular proteinsPredicted membrane proteins
Protein Function
Predicted intracellular proteins
Transmembrane
99..119; Helical; 150..170; Helical
Transmembrane Count
2
Ensembl
Entrez Gene Symbol
Gene Synonym (3)
C20orf108dJ1167H4.1DKFZP434A1114
Gene Description
Family with sequence similarity 210 member B
Chromosome
20
Position
56358974-56368663
Supporting publications (n)
3
EVMP confidence score
0.50
Function & Pathway6
Protein Function
Predicted intracellular proteins
Cellular Component (3)
Molecular Function
Biological Process (3)
Canonical Pathways
M106 Pid hnf3b pathway
Mediation Categories
Immune mediation
Relations & Evidence12
Ligand-Receptor Signaling (10)
10 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
| transmembrane | transmembrane | UniProt_location | No | No | No | No | No |
| transmembrane | transmembrane | UniProt_topology | No | No | No | No | No |
| transmembrane | transmembrane | UniProt_keyword | No | No | No | No | No |
| transmembrane | transmembrane | Ramilowski_location | No | No | No | No | No |
| transmembrane | transmembrane | OmniPath | No | No | No | No | No |
| transmembrane | transmembrane_predicted | Phobius | No | No | No | No | No |
Protein Complex Composition (1)
1 record.
| Component Name | Component Gene Symbols | Component UniProt ID | Stoichiometry | Database | Database IDs | References |
|---|---|---|---|---|---|---|
| CABP5CCNA2CCNE1CCNHCDK1CDK2CDK6CDKN1BCKS1BEP300FAM210BGLALMO4SKP2 | P06280P06493P20248P24864P24941P46527P51946P61024P61968Q00534Q09472Q13309Q96KR6Q9NP86 | 1:1:1:1:1:1:1:1:1:1:1:1:1:1 | NetworkBlastCompleat | Compleat:HC9829 |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Mass spectrometryMass spectrometry [LTQ-FT Ultra]R Sequencing | 1 | 22329422 |
Sequence, Structure & Domains8
Sequences
Length
192
Mass
20,424
Sequence
MAGLLALLGPAGRVGARVRPRATWLLGATAPCAPPPLALALLPPRLDARLLRTARGDCRGHQDPSQATGTTGSSVSCTEEKKQSKSQQLKKIFQEYGTVGVSLHIGISLISLGIFYMVVSSGVDMPAILLKLGFKESLVQSKMAAGTSTFVVAYAIHKLFAPVRISITLVSVPLIVRYFRKVGFFKPPAAKP
Domain & Motif Annotations
Compositional Bias
63..77; Polar residues
Domain (FT)
80..191; DUF1279
Region
57..80; Disordered
Protein Families
FAM210 family
Sequence Similarities
Belongs to the FAM210 family.
Clinical Relevance2
Disease Involvement
Tumor suppressor
Antibody
Supporting Publications3
| PMID | Title | Abstract |
|---|---|---|
| 31617158 | Proteomic profiling of peritoneal dialysis effluent-derived extracellular vesicles: a longitudinal study. | No abstract available |
| 37322475 | Comprehensive profiling of extracellular vesicles in uveitis and scleritis enables biomarker discovery and mechanism exploration. | No abstract available |
| 40465195 | Extracellular vesicle proteomics uncovers energy metabolism, complement system, and endoplasmic reticulum stress response dysregulation postexercise in males with myalgic encephalomyelitis/chronic fatigue syndrome. | No abstract available |