Protein detail
PGRP4
Peptidoglycan recognition protein 4 (Peptidoglycan recognition protein I-beta) (PGLYRPIbeta) (PGRP-I-beta) (Peptidoglycan recognition protein intermediate beta)
Protein symbol PGRP4 | UniProt ID | EVMP score 0.38 |
Frequency 1 | Transmembrane count | Protein classification |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Peptidoglycan recognition protein 4 (Peptidoglycan recognition protein I-beta) (PGLYRPIbeta) (PGRP-I-beta) (Peptidoglycan recognition protein intermediate beta)
Protein Function
Predicted secreted proteins
Ensembl
Entrez Gene Symbol
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Cell SpecificEsophageal apical cells
Function & Pathway
Protein Function
Predicted secreted proteins
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Immune mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
9 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| ecm | ecm | MatrixDB | Yes | No | Yes | No | No |
| ecm | ecm | OmniPath | Yes | No | Yes | No | No |
| extracellular | extracellular | OmniPath | No | No | Yes | No | No |
| peptidoglycan | secreted_receptor | HGNC | Yes | No | Yes | No | No |
| secreted_receptor | secreted_receptor | OmniPath | Yes | No | Yes | No | No |
| secreted | secreted | UniProt_keyword | No | No | Yes | No | No |
| secreted | secreted | UniProt_location | No | No | Yes | No | No |
| secreted | secreted | HPA_secretome | No | No | Yes | No | No |
| secreted | secreted | OmniPath | No | No | Yes | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
Sequence, Structure & Domains
Sequences
Length
373
Mass
40,620
Sequence
MLPWLLVFSALGIQAWGDSSWNKTQAKQVSEGLQYLFENISQLTEKGLPTDVSTTVSRKAWGAEAVGCSIQLTTPVNVLVIHHVPGLECHDQTVCSQRLRELQAHHVHNNSGCDVAYNFLVGDDGRVYEGVGWNIQGVHTQGYNNISLGFAFFGTKKGHSPSPAALSAMENLITYAVQKGHLSSSYVQPLLGKGENCLAPRQKTSLKKACPGVVPRSVWGARETHCPRMTLPAKYGIIIHTAGRTCNISDECRLLVRDIQSFYIDRLKSCDIGYNFLVGQDGAIYEGVGWNVQGSSTPGYDDIALGITFMGTFTGIPPNAAALEAAQDLIQCAMVKGYLTPNYLLVGHSDVARTLSPGQALYNIISTWPHFKH
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q96LB8-1; Sequence=Displayed; Name=2; IsoId=Q96LB8-2; Sequence=VSP_024388
Alternative Sequence
47..50; Missing (in isoform 2)
3D Structural Models
Turn
298..300
Helix
216..219; 249..265; 301..303; 320..335; 348..351; 359..365
Beta Strand
212..214; 231..240; 275..278; 284..288; 290..292; 304..311; 314..316; 338..347; 352..354
3D Structure
X-ray crystallography (2)
Domain & Motif Annotations
Domain (FT)
74..212; N-acetylmuramoyl-L-alanine amidase 1; 235..358; N-acetylmuramoyl-L-alanine amidase 2
Region
293..302; Interaction with murein; 353..354; Interaction with murein
Protein Families
N-acetylmuramoyl-L-alanine amidase 2 family
Sequence Similarities
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
Clinical Relevance
Drugs