Protein detail

F161B

Protein FAM161B

Entry name F161B	UniProt ID Q96MY7	EVMP score 0.38
Frequency 3	Transmembrane count	Protein classification Predicted intracellular proteins

EVMP score: annotation confidence score.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information

Protein Names

Protein FAM161B

Protein Class

Predicted intracellular proteins

Protein Function

Predicted intracellular proteins

Ensembl

ENSG00000156050

Entrez Gene Symbol

FAM161B

Gene Synonym

C14orf44FLJ31697

Gene Description

FAM161 centrosomal protein B

Chromosome

Position

73931501-73950414

Frequency

EVMP Score

0.38

Fluorescence & Localization

Function & Pathway

Protein Function

Predicted intracellular proteins

Cellular Component

Molecular Function

GO:0005515 protein binding

Biological Process

Mediation Categories

Other mediation

Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

3 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
intracellular	intracellular	ComPPI	No	No	No	No	No
intracellular	intracellular	GO_Intercell	No	No	No	No	No
intracellular	intracellular	OmniPath	No	No	No	No	No

Regulatory Interaction Network

0 records.

Protein Complex Composition

1 record.

Component Name	Component Gene Symbols	Component UniProt ID	Stoichiometry	Database	Database IDs	References
	C4BPA CBFB CCS FAM161B RGN SOD1 TXN TXN2	O14618 P00441 P04003 P10599 Q13951 Q15493 Q96MY7 Q99757	0:0:0:0:0:0:0:0	hu.MAP

Isolation & Detection Technology

1 record.

EV Isolation Method	Detection Method	Number of References	References
	Mass spectrometry	0

Sequence, Structure & Domains

Sequences

Length

647

Mass

73,647

Sequence

MTVGRPEGAPGGAEGSRQIFPPESFADTEAGEELSGDGLVLPRASKLDEFLSPEEEIDSTSDSTGSIYQNLQELKQKGRWCLLESLFQSDPESDENLSEDEEDLESFFQDKDRGMVQVQCPQALRCGSTRRCSSLNNLPSNIPRPQTQPPSGSRPPSQHRSVSSWASSITVPRPFRMTLREARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQPPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKADESIQWLEIHKKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEELSHQSPENLVSLA

Alternative Products

Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q96MY7-1; Sequence=Displayed; Name=2; IsoId=Q96MY7-2; Sequence=VSP_046328

Alternative Sequence

1; M -> MRGENRPIGKRTLPPRAGWIGGCPGSQPDAKARKGWTLAPHSSRCHRCCHYRCHCRCCLCPAEM (in isoform 2)

3D Structural Models

Domain & Motif Annotations

Compositional Bias

91..105; Acidic residues; 332..350; Polar residues; 590..602; Basic and acidic residues; 637..647; Polar residues

Coiled Coil

262..292; 510..546

Region

1..39; Disordered; 89..110; Disordered; 135..167; Disordered; 332..352; Disordered; 388..439; Disordered; 583..647; Disordered

Protein Families

FAM161 family

Sequence Similarities

Belongs to the FAM161 family.

Clinical Relevance

Antibody

HPA019125