Protein detail

F161B

Protein FAM161B

Entry name F161B	UniProt ID Q96MY7	EVMP confidence score 0.38
Supporting publications (n) 3	Transmembrane count	Protein classification Predicted intracellular proteins

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information11

Protein Names

Protein FAM161B

Protein Class

Predicted intracellular proteins

Protein Function

Predicted intracellular proteins

Ensembl

ENSG00000156050

Entrez Gene Symbol

FAM161B

Gene Synonym (2)

C14orf44FLJ31697

Gene Description

FAM161 centrosomal protein B

Chromosome

Position

73931501-73950414

Supporting publications (n)

EVMP confidence score

0.38

Function & Pathway5

Protein Function

Predicted intracellular proteins

Cellular Component (3)

Molecular Function

GO:0005515 protein binding

Biological Process (3)

Mediation Categories

Other mediation

Relations & Evidence5

Ligand-Receptor Signaling (3)

3 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
intracellular	intracellular	ComPPI	No	No	No	No	No
intracellular	intracellular	GO_Intercell	No	No	No	No	No
intracellular	intracellular	OmniPath	No	No	No	No	No

Protein Complex Composition (1)

1 record.

Component Name	Component Gene Symbols	Component UniProt ID	Stoichiometry	Database	Database IDs	References
	C4BPA CBFB CCS FAM161B RGN SOD1 TXN TXN2	O14618 P00441 P04003 P10599 Q13951 Q15493 Q96MY7 Q99757	0:0:0:0:0:0:0:0	hu.MAP

Isolation & Detection Technology (1)

1 record.

EV Isolation Method	Detection Method	Number of References	References
	Mass spectrometry	0

Sequence, Structure & Domains10

Sequences

Length

647

Mass

73,647

Sequence

MTVGRPEGAPGGAEGSRQIFPPESFADTEAGEELSGDGLVLPRASKLDEFLSPEEEIDSTSDSTGSIYQNLQELKQKGRWCLLESLFQSDPESDENLSEDEEDLESFFQDKDRGMVQVQCPQALRCGSTRRCSSLNNLPSNIPRPQTQPPSGSRPPSQHRSVSSWASSITVPRPFRMTLREARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKATRRIPKSILEPALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQPPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKADESIQWLEIHKKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEELSHQSPENLVSLA

Alternative Products

Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q96MY7-1; Sequence=Displayed; Name=2; IsoId=Q96MY7-2; Sequence=VSP_046328

Alternative Sequence

1; M -> MRGENRPIGKRTLPPRAGWIGGCPGSQPDAKARKGWTLAPHSSRCHRCCHYRCHCRCCLCPAEM (in isoform 2)

Domain & Motif Annotations

Compositional Bias

91..105; Acidic residues; 332..350; Polar residues; 590..602; Basic and acidic residues; 637..647; Polar residues

Coiled Coil

262..292; 510..546

Region

1..39; Disordered; 89..110; Disordered; 135..167; Disordered; 332..352; Disordered; 388..439; Disordered; 583..647; Disordered

Protein Families

FAM161 family

Sequence Similarities

Belongs to the FAM161 family.

Clinical Relevance1

Antibody

HPA019125

Supporting Publications3

PMID	Title	Abstract
32231660	Natural-Killer-Derived Extracellular Vesicles: Immune Sensors and Interactors.	No abstract available
39104279	A Predictive Model for Initial Platinum-Based Chemotherapy Efficacy in Patients with Postoperative Epithelial Ovarian Cancer Using Tissue-Derived Small Extracellular Vesicles.	No abstract available
40829696	Mining the plasma proteome: Evaluation of enrichment methods for depth and reproducibility.	No abstract available