Protein detail
CF418
Cilia- and flagella-associated protein 418
Entry name CF418 | UniProt ID | EVMP score 0.38 |
Frequency 2 | Transmembrane count | Protein classification Disease related genesHuman disease related genesPredicted intracellular proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Cilia- and flagella-associated protein 418
Protein Class
Disease related genesHuman disease related genesPredicted intracellular proteins
Protein Function
- Disease related genes
- Predicted intracellular proteins
- Human disease related genes:Nervous system diseases:Eye disease
- Human disease related genes:Congenital disorders of metabolism:Other congenital disorders of metabolism
Ensembl
Entrez Gene Symbol
Gene Synonym
BBS21C8orf37CORD16FAP418FLJ30600MOT25RP64
Gene Description
Cilia and flagella associated protein 418
Chromosome
8
Position
95244913-95269201
Frequency
2
EVMP Score
0.38
Fluorescence & Localization
Function & Pathway
Protein Function
- Disease related genes
- Predicted intracellular proteins
- Human disease related genes:Nervous system diseases:Eye disease
- Human disease related genes:Congenital disorders of metabolism:Other congenital disorders of metabolism
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Sequence, Structure & Domains
Sequences
Length
207
Mass
23,381
Sequence
MAEDLDELLDEVESKFCTPDLLRRGMVEQPKGCGGGTHSSDRNQAKAKETLRSTETFKKEDDLDSLINEILEEPNLDKKPSKLKSKSSGNTSVRASIEGLGKSCSPVYLGGSSIPCGIGTNISWRACDHLRCIACDFLVVSYDDYMWDKSCDYLFFRNNMPEFHKLKAKLIKKKGTRAYACQCSWRTIEEVTDLQTDHQLRWVCGKH
3D Structural Models
Domain & Motif Annotations
Compositional Bias
39..52; Basic and acidic residues
Region
1..75; Required for interaction with FAM161A; 26..52; Disordered
Clinical Relevance
Disease Involvement
Bardet-Biedl syndromeCiliopathyCone-rod dystrophyDisease variantObesityRetinitis pigmentosa
Antibody