Protein detail
CF418
Cilia- and flagella-associated protein 418
Entry name CF418 | UniProt ID | EVMP confidence score 0.53 |
Supporting publications (n) 2 | Transmembrane count | Protein classification Disease related genesHuman disease related genesPredicted intracellular proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Cilia- and flagella-associated protein 418
Protein Class (3)
Disease related genesHuman disease related genesPredicted intracellular proteins
Protein Function (4)
- Disease related genes
- Predicted intracellular proteins
- Human disease related genes:Nervous system diseases:Eye disease
- Human disease related genes:Congenital disorders of metabolism:Other congenital disorders of metabolism
Ensembl
Entrez Gene Symbol
Gene Synonym (7)
BBS21C8orf37CORD16FAP418FLJ30600MOT25RP64
Gene Description
Cilia and flagella associated protein 418
Chromosome
8
Position
95244913-95269201
Supporting publications (n)
2
EVMP confidence score
0.53
Function & Pathway
Protein Function (4)
- Disease related genes
- Predicted intracellular proteins
- Human disease related genes:Nervous system diseases:Eye disease
- Human disease related genes:Congenital disorders of metabolism:Other congenital disorders of metabolism
Cellular Component (6)
Molecular Function
Biological Process (3)
Mediation Categories
Other mediation
Relations & Evidence5
Ligand-Receptor Signaling (4)
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | |||||
| intracellular | intracellular | GO_Intercell | |||||
| intracellular | intracellular | UniProt_location | |||||
| intracellular | intracellular | OmniPath |
Sequence, Structure & Domains
Sequences
Length
207
Mass
23,381
Sequence
MAEDLDELLDEVESKFCTPDLLRRGMVEQPKGCGGGTHSSDRNQAKAKETLRSTETFKKEDDLDSLINEILEEPNLDKKPSKLKSKSSGNTSVRASIEGLGKSCSPVYLGGSSIPCGIGTNISWRACDHLRCIACDFLVVSYDDYMWDKSCDYLFFRNNMPEFHKLKAKLIKKKGTRAYACQCSWRTIEEVTDLQTDHQLRWVCGKH
Domain & Motif Annotations
Compositional Bias
39..52; Basic and acidic residues
Region
1..75; Required for interaction with FAM161A; 26..52; Disordered
Clinical Relevance
Disease Involvement (6)
Bardet-Biedl syndromeCiliopathyCone-rod dystrophyDisease variantObesityRetinitis pigmentosa
Related Diseases (4)
Antibody
Supporting Publications2
| PMID | Title | Related sentences |
|---|---|---|
| 38731868 | The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer. | No related sentences available |
| 40784529 | Serum-derived exosome proteomics unveils the distinct and adjustable nature of the dampness constitution in traditional Chinese medicine. | No related sentences available |