Protein detail

CIB3

Calcium and integrin-binding family member 3 (Kinase-interacting protein 3) (KIP 3)

Entry name
CIB3
UniProt ID
EVMP confidence score
0.38
Supporting publications (n)
1
Transmembrane count
Protein classification
Predicted intracellular proteins
EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information11
Protein Names
Calcium and integrin-binding family member 3 (Kinase-interacting protein 3) (KIP 3)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Entrez Gene Symbol
Gene Synonym
KIP3
Gene Description
Calcium and integrin binding family member 3
Chromosome
19
Position
16161368-16173525
Supporting publications (n)
1
EVMP confidence score
0.38
Fluorescence & Localization4
CIB3 fluorescence
Tissue SpecificcervixCell SpecificEsophageal apical cellsSingle-Nuclei Brain Specificdeep-layer intratelencephalic
Function & Pathway4
Relations & Evidence4

Ligand-Receptor Signaling (2)

2 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo

Protein Complex Composition (1)

1 record.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
CIB3Q96Q772PDBPDB:6wu5PDB:6wu7

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationDensity Gradient CentrifugationSize Exclusion ChromatographyMass spectrometry439940641363985643481790638321535
Sequence, Structure & Domains10

Sequences

Length
187
Mass
21,802
Sequence
MGNKQTVFTHEQLEAYQDCTFFTRKEIMRLFYRYQDLAPQLVPLDYTTCPDVKVPYELIGSMPELKDNPFRQRIAQVFSEDGDGHMTLDNFLDMFSVMSEMAPRDLKAYYAFKIYDFNNDDYICAWDLEQTVTKLTRGGLSAEEVSLVCEKVLDEADGDHDGRLSLEDFQNMILRAPDFLSTFHIRI
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q96Q77-1; Sequence=Displayed; Name=2; IsoId=Q96Q77-2; Sequence=VSP_055509
Alternative Sequence
18..66; Missing (in isoform 2)

3D Structural Models

Turn
39..41; 63..67; 136..138
Helix
10..19; 24..37; 46..48; 56..60; 71..78; 88..98; 104..115; 125..135; 142..156; 166..174; 181..183
Beta Strand
82..84; 120..123; 160..164
3D Structure
X-ray crystallography (3)

Domain & Motif Annotations

Domain (FT)
66..101; EF-hand 1; 103..138; EF-hand 2; 144..179; EF-hand 3
Clinical Relevance1
Supporting Publications1
PMIDTitleAbstract
32396726Plasma-Derived Extracellular Vesicle Phosphoproteomics through Chemical Affinity Purification.No abstract available