Protein detail
CD180
CD180 antigen (Lymphocyte antigen 64) (Radioprotective 105 kDa protein) (CD antigen CD180)
Entry name CD180 | UniProt ID | EVMP confidence score 0.53 |
Supporting publications (n) 1 | Transmembrane count 1 | Protein classification CD markersPredicted membrane proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
CD180 antigen (Lymphocyte antigen 64) (Radioprotective 105 kDa protein) (CD antigen CD180)
Protein Class (2)
CD markersPredicted membrane proteins
Protein Function
CD markers
Transmembrane
627..650; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym (3)
LY64Ly78RP105
Gene Description
CD180 molecule
Chromosome
5
Position
67179613-67196799
Supporting publications (n)
1
EVMP confidence score
0.53
Fluorescence & Localization
Tissue SpecificintestineCell SpecificCholangiocytes
Function & Pathway
Protein Function
CD markers
Cellular Component (6)
Molecular Function
Biological Process (3)
Mediation Categories
Immune mediation
Relations & Evidence39
Ligand-Receptor Signaling (37)
37 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| receptor | receptor | iTALK | Yes | Yes | |||
| receptor | receptor | Almen2009 | Yes | Yes | |||
| receptor | receptor | EMBRACE | Yes | Yes | |||
| transmembrane | transmembrane_predicted | Phobius | Yes | ||||
| transmembrane_phobius | transmembrane_predicted | Almen2009 | Yes | ||||
| transmembrane_sosui | transmembrane_predicted | Almen2009 | Yes | ||||
| transmembrane_tmhmm | transmembrane_predicted | Almen2009 | Yes |
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Protein Complex Composition (1)
Sequence, Structure & Domains
Sequences
Length
661
Mass
74,179
Sequence
MAFDVSCFFWVVLFSAGCKVITSWDQMCIEKEANKTYNCENLGLSEIPDTLPNTTEFLEFSFNFLPTIHNRTFSRLMNLTFLDLTRCQINWIHEDTFQSHHQLSTLVLTGNPLIFMAETSLNGPKSLKHLFLIQTGISNLEFIPVHNLENLESLYLGSNHISSIKFPKDFPARNLKVLDFQNNAIHYISREDMRSLEQAINLSLNFNGNNVKGIELGAFDSTIFQSLNFGGTPNLSVIFNGLQNSTTQSLWLGTFEDIDDEDISSAMLKGLCEMSVESLNLQEHRFSDISSTTFQCFTQLQELDLTATHLKGLPSGMKGLNLLKKLVLSVNHFDQLCQISAANFPSLTHLYIRGNVKKLHLGVGCLEKLGNLQTLDLSHNDIEASDCCSLQLKNLSHLQTLNLSHNEPLGLQSQAFKECPQLELLDLAFTRLHINAPQSPFQNLHFLQVLNLTYCFLDTSNQHLLAGLPVLRHLNLKGNHFQDGTITKTNLLQTVGSLEVLILSSCGLLSIDQQAFHSLGKMSHVDLSHNSLTCDSIDSLSHLKGIYLNLAANSINIISPRLLPILSQQSTINLSHNPLDCTCSNIHFLTWYKENLHKLEGSEETTCANPPSLRGVKLSDVKLSCGITAIGIFFLIVFLLLLAILLFFAVKYLLRWKYQHI
3D Structural Models
Turn
33..35; 70..75; 94..99; 118..121; 195..198; 216..221; 242..244; 265..268; 291..294; 365..368; 389..391; 413..418; 440..443; 462..467; 513..518; 618..620
Helix
140..142; 190..194; 235..241; 269..273; 296..299; 336..339; 341..343; 482..484; 491..494; 534..540; 563..567; 583..585; 586..594
Beta Strand
29..32; 36..38; 57..59; 66..68; 80..83; 105..107; 129..131; 153..155; 177..179; 200..205; 223..228; 246..251; 274..280; 286..288; 301..304; 325..327; 349..351; 374..376; 384..388; 400..402; 409..411; 424..426; 449..451; 473..475; 500..502; 524..526; 547..549; 569..573; 598..600; 607..613
3D Structure
X-ray crystallography (1)
Domain & Motif Annotations
Repeat
54..75; LRR 1; 78..99; LRR 2; 102..123; LRR 3; 126..147; LRR 4; 150..171; LRR 5; 174..195; LRR 6; 201..221; LRR 7; 275..296; LRR 8; 299..320; LRR 9; 322..343; LRR 10; 346..366; LRR 11; 371..391; LRR 12; 397..418; LRR 13; 421..442; LRR 14; 446..466; LRR 15; 470..493; LRR 16; 497..518; LRR 17; 521..544; LRR 18; 546..564; LRR 19
Domain (FT)
33..53; LRRNT; 577..627; LRRCT
Protein Families
Toll-like receptor family
Sequence Similarities
Belongs to the Toll-like receptor family.
Clinical Relevance
Antibody
Interaction Protein
ENSG00000112799
Interaction Count
1
Interaction Dataset
intact_biogrid
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 27487081 | Comparative Proteomic Analysis of Extracellular Vesicles Isolated by Acoustic Trapping or Differential Centrifugation. | No related sentences available |