Protein detail
RHXF2
Rhox homeobox family member 2 (Paired-like homeobox protein PEPP-2) (Testis homeobox gene 1)
Protein symbol RHXF2 | UniProt ID | EVMP score 0.38 |
Frequency 1 | Transmembrane count | Protein classification Predicted intracellular proteinsTranscription factors |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Rhox homeobox family member 2 (Paired-like homeobox protein PEPP-2) (Testis homeobox gene 1)
Protein Class
Predicted intracellular proteinsTranscription factors
Protein Function
- Transcription factors:Helix-turn-helix domains
- Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
CT107PEPP-2PEPP2THG1
Gene Description
Rhox homeobox family member 2
Chromosome
X
Position
120158613-120165630
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Tissue SpecificepididymisCell SpecificB-cellsSingle-Nuclei Brain Specificcentral nervous system macrophageBlood Cell Specificmemory B-cellSecretome LocationSecreted to bloodSecretome FunctionEnzyme
Function & Pathway
Protein Function
- Transcription factors:Helix-turn-helix domains
- Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
6 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
| transmembrane | transmembrane | Ramilowski_location | No | No | No | No | No |
| transmembrane | transmembrane | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationSize Exclusion ChromatographyImmunoaffinity Capture | Mass spectrometryWestern blottingR SequencingFlow cytometryMORPHELISA | 11 | 3994949039873726387318682680191927894104383215353849095840098346386984203132059138136601 |
Sequence, Structure & Domains
Sequences
Length
288
Mass
31,692
Sequence
MEPPDQCSQYMTSLLSPAVDDEKELQDMNAMVLSLTEEVKEEEEDAQPEPEQGTAAGEKLKSAGAQGGEEKDGGGEEKDGGGAGVPGHLWEGDLEGTSGSDGNVEDSDQSEKEPGQQYSRPQGAVGGLEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWDHSHSSSLCFPMPPFPPPSLPLPLMLLPPMPPAGQAEFGPFPFVIVPSFTFPNV
3D Structural Models
Domain & Motif Annotations
Compositional Bias
39..48; Acidic residues; 68..80; Basic and acidic residues
Motif
186..195; Nuclear localization signal
Region
16..136; Disordered
Protein Families
- Paired-like homeobox family
- PEPP subfamily
Sequence Similarities
Belongs to the paired-like homeobox family. PEPP subfamily.