Protein detail
ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A (EC 3.6.5.-) (Cobalamin synthase W domain-containing protein 1) (COBW domain-containing protein 1) (NPC-A-6 COBW domain-containing protein 1) (NPC-A-6)
Protein symbol ZNG1A | UniProt ID | EVMP score 0.38 |
Frequency 1 | Transmembrane count | Protein classification Disease related genesPredicted intracellular proteins |
Basic Information
Protein Names
Zinc-regulated GTPase metalloprotein activator 1A (EC 3.6.5.-) (Cobalamin synthase W domain-containing protein 1) (COBW domain-containing protein 1) (NPC-A-6 COBW domain-containing protein 1) (NPC-A-6)
Protein Class
Disease related genesPredicted intracellular proteins
Protein Function
- Disease related genes
- Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
CBWD1
Gene Description
Zn regulated GTPase metalloprotein activator 1A
Chromosome
9
Position
120837-179147
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Function & Pathway
Protein Function
- Disease related genes
- Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Sequence, Structure & Domains
Sequences
Length
395
Mass
44,068
Sequence
MLPAVGSADEEEDPAEEDCPELVPIETTQSEEEEKSGLGAKIPVTIITGYLGAGKTTLLNYILTEQHSKRVAVILNEFGEGSALEKSLAVSQGGELYEEWLELRNGCLCCSVKDSGLRAIENLMQKKGKFDYILLETTGLADPGAVASMFWVDAELGSDIYLDGIITIVDSKYGLKHLTEEKPDGLINEATRQVALADAILINKTDLVPEEDVKKLRTTIRSINGLGQILETQRSRVDLSNVLDLHAFDSLSGISLQKKLQHVPGTQPHLDQSIVTITFEVPGNAKEEHLNMFIQNLLWEKNVRNKDNHCMEVIRLKGLVSIKDKSQQVIVQGVHELYDLEETPVSWKDDTERTNRLVLLGRNLDKDILKQLFIATVTETEKQWTTRFQEDQVCT
Alternative Products
Event=Alternative splicing; Named isoforms=4; Name=1; IsoId=Q9BRT8-1; Sequence=Displayed; Name=2; IsoId=Q9BRT8-2; Sequence=VSP_019731, VSP_019732; Name=3; IsoId=Q9BRT8-3; Sequence=VSP_019734; Name=4; IsoId=Q9BRT8-4; Sequence=VSP_019733
Alternative Sequence
1..36; Missing (in isoform 2); 37..51; GLGAKIPVTIITGYL -> MYFKRAARAFPVLLT (in isoform 2); 114..395; Missing (in isoform 4); 236..254; Missing (in isoform 3)
3D Structural Models
Domain & Motif Annotations
Compositional Bias
8..20; Acidic residues
Motif
17..24; psi-PxLVp motif; 107..110; CXCC motif
Domain (FT)
274..377; CobW C-terminal
Region
1..22; Disordered
Protein Families
- SIMIBI class G3E GTPase family
- ZNG1 subfamily
Sequence Similarities
Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.