Protein detail
UBAC1
Ubiquitin-associated domain-containing protein 1 (UBA domain-containing protein 1) (Glialblastoma cell differentiation-related protein 1) (Kip1 ubiquitination-promoting complex protein 2)
Entry name UBAC1 | UniProt ID | EVMP score 0.38 |
Frequency 3 | Transmembrane count | Protein classification Predicted intracellular proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Ubiquitin-associated domain-containing protein 1 (UBA domain-containing protein 1) (Glialblastoma cell differentiation-related protein 1) (Kip1 ubiquitination-promoting complex protein 2)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
GBDR1KPC2UBADC1
Gene Description
UBA domain containing 1
Chromosome
9
Position
135932969-135961373
Frequency
3
EVMP Score
0.38
Fluorescence & Localization
Cell SpecificCardiomyocytes
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Reactome
Mediation Categories
Immune mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion ChromatographyImmunoaffinity CaptureMicrofluidics-Based Methods | Mass spectrometry | 15 | 347540073822545338556629104515084094531740545963377027152680191927723984305502873857600240098346384890294009145534355211 |
Sequence, Structure & Domains
Sequences
Length
405
Mass
45,338
Sequence
MFVQEEKIFAGKVLRLHICASDGAEWLEEATEDTSVEKLKERCLKHCAHGSLEDPKSITHHKLIHAASERVLSDARTILEENIQDQDVLLLIKKRAPSPLPKMADVSAEEKKKQDQKAPDKEAILRATANLPSYNMDRAAVQTNMRDFQTELRKILVSLIEVAQKLLALNPDAVELFKKANAMLDEDEDERVDEAALRQLTEMGFPENRATKALQLNHMSVPQAMEWLIEHAEDPTIDTPLPGQAPPEAEGATAAASEAAAGASATDEEARDELTEIFKKIRRKREFRADARAVISLMEMGFDEKEVIDALRVNNNQQNAACEWLLGDRKPSPEELDKGIDPDSPLFQAILDNPVVQLGLTNPKTLLAFEDMLENPLNSTQWMNDPETGPVMLQISRIFQTLNRT
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9BSL1-1; Sequence=Displayed; Name=2; IsoId=Q9BSL1-2; Sequence=VSP_062527
Alternative Sequence
1..102; Missing (in isoform 2)
3D Structural Models
Helix
194..203; 207..216; 221..230; 231..233
Beta Strand
189..191
3D Structure
NMR spectroscopy (1)
Domain & Motif Annotations
Compositional Bias
108..120; Basic and acidic residues; 246..265; Low complexity
Domain (CC)
The UBA domains recognize and bind polyubiquitinated proteins.
Domain (FT)
14..98; Ubiquitin-like; 187..231; UBA 1; 288..328; UBA 2; 353..392; STI1
Region
101..120; Disordered; 235..271; Disordered
Clinical Relevance
Antibody
Interaction Protein
ENSG00000150991ENSG00000164068ENSG00000170315
Interaction Count
3
Interaction Dataset
intact_biogrid