Protein detail

CNPY3

Protein canopy homolog 3 (CTG repeat protein 4a) (Expanded repeat-domain protein CAG/CTG 5) (Protein associated with TLR4) (Trinucleotide repeat-containing gene 5 protein)

Entry name
CNPY3
UniProt ID
Q9BT09
EVMP confidence score
0.53
Supporting publications (n)
1
Transmembrane count
Protein classification
Disease related genesHuman disease related genesPredicted intracellular proteins
Basic Information
Protein Names
Protein canopy homolog 3 (CTG repeat protein 4a) (Expanded repeat-domain protein CAG/CTG 5) (Protein associated with TLR4) (Trinucleotide repeat-containing gene 5 protein)
Protein Class (3)
Disease related genesHuman disease related genesPredicted intracellular proteins
Protein Function (3)
  • Human disease related genes:Nervous system diseases:Epilepsy
  • Disease related genes
  • Predicted intracellular proteins
Ensembl
ENSG00000137161
Entrez Gene Symbol
CNPY3
Gene Synonym (2)
CAG4ATNRC5
Gene Description
Canopy FGF signaling regulator 3
Chromosome
6
Position
42929480-42939294
Supporting publications (n)
1
EVMP confidence score
0.53
Fluorescence & Localization
CNPY3 fluorescence
Tissue SpecifictestisCell SpecificLate spermatids
Function & Pathway
Protein Function (3)
  • Human disease related genes:Nervous system diseases:Epilepsy
  • Disease related genes
  • Predicted intracellular proteins
Cellular Component
GO:0005788 endoplasmic reticulum lumen
Molecular Function (2)
Biological Process (3)
Reactome (3)
Canonical Pathways (3)
  • M5883 Naba secreted factors
  • M5885 Naba matrisome associated
  • M5889 Naba matrisome
Mediation Categories
Immune mediation
Relations & Evidence5

Ligand-Receptor Signaling (4)

4 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPI
intracellularintracellularGO_Intercell
intracellularintracellularUniProt_location
intracellularintracellularOmniPath

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyImmunoaffinity CaptureOlink Proximity Extension Assay；Mass Spectrometry23370951040098346
Sequence, Structure & Domains

Sequences

Length
278
Mass
30,748
Sequence
MDSMPEPASRCLLLLPLLLLLLLLLPAPELGPSQAGAEENDWVRLPSKCEVCKYVAVELKSAFEETGKTKEVIGTGYGILDQKASGVKYTKSDLRLIEVTETICKRLLDYSLHKERTGSNRFAKGMSETFETLHNLVHKGVKVVMDIPYELWNETSAEVADLKKQCDVLVEEFEEVIEDWYRNHQEEDLTEFLCANHVLKGKDTSCLAEQWSGKKGDTAALGGKKSKKKSSRAKAAGGRSSSSKQRKELGGLEGDPSPEEDEGIQKASPLTHSPPDEL
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9BT09-1; Sequence=Displayed; Name=2; IsoId=Q9BT09-2; Sequence=VSP_030132, VSP_030133
Alternative Sequence
51..54; VCKY -> GTCG (in isoform 2); 55..278; Missing (in isoform 2)

Domain & Motif Annotations

Compositional Bias
233..243; Low complexity
Coiled Coil
153..179
Domain (FT)
47..271; Saposin B-type
Region
215..278; Disordered
Protein Families
Canopy family
Sequence Similarities
Belongs to the canopy family.
Clinical Relevance
Disease Involvement (2)
Disease variantEpilepsy
Related Diseases
Epilepsy
Antibody
HPA016560
Supporting Publications1
PMIDTitleRelated sentences
32218180Proteomic Analysis of Blood Exosomes from Healthy Females and Breast Cancer Patients Reveals an Association between Different Exosomal Bioactivity on Non-tumorigenic Epithelial Cell and Breast Cancer Cell Migration in Vitro.No related sentences available