Protein detail

CNPY3

Protein canopy homolog 3 (CTG repeat protein 4a) (Expanded repeat-domain protein CAG/CTG 5) (Protein associated with TLR4) (Trinucleotide repeat-containing gene 5 protein)

Protein symbol
CNPY3
UniProt ID
EVMP score
0.38
Frequency
1
Transmembrane count
Protein classification
Disease related genesHuman disease related genesPredicted intracellular proteins
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Protein canopy homolog 3 (CTG repeat protein 4a) (Expanded repeat-domain protein CAG/CTG 5) (Protein associated with TLR4) (Trinucleotide repeat-containing gene 5 protein)
Protein Class
Disease related genesHuman disease related genesPredicted intracellular proteins
Protein Function
  • Human disease related genes:Nervous system diseases:Epilepsy
  • Disease related genes
  • Predicted intracellular proteins
Entrez Gene Symbol
Gene Synonym
CAG4ATNRC5
Gene Description
Canopy FGF signaling regulator 3
Chromosome
6
Position
42929480-42939294
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Tissue SpecifictestisCell SpecificLate spermatids
Function & Pathway
Protein Function
  • Human disease related genes:Nervous system diseases:Epilepsy
  • Disease related genes
  • Predicted intracellular proteins
Canonical Pathways
  • M5883 Naba secreted factors
  • M5885 Naba matrisome associated
  • M5889 Naba matrisome
Mediation Categories
Immune mediation
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

4 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularGO_IntercellNoNoNoNoNo
intracellularintracellularUniProt_locationNoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo

Regulatory Interaction Network

0 records.

Protein Complex Composition

0 records.

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyImmunoaffinity CaptureOlink Proximity Extension Assay;Mass Spectrometry23370951040098346
Sequence, Structure & Domains

Sequences

Length
278
Mass
30,748
Sequence
MDSMPEPASRCLLLLPLLLLLLLLLPAPELGPSQAGAEENDWVRLPSKCEVCKYVAVELKSAFEETGKTKEVIGTGYGILDQKASGVKYTKSDLRLIEVTETICKRLLDYSLHKERTGSNRFAKGMSETFETLHNLVHKGVKVVMDIPYELWNETSAEVADLKKQCDVLVEEFEEVIEDWYRNHQEEDLTEFLCANHVLKGKDTSCLAEQWSGKKGDTAALGGKKSKKKSSRAKAAGGRSSSSKQRKELGGLEGDPSPEEDEGIQKASPLTHSPPDEL
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9BT09-1; Sequence=Displayed; Name=2; IsoId=Q9BT09-2; Sequence=VSP_030132, VSP_030133
Alternative Sequence
51..54; VCKY -> GTCG (in isoform 2); 55..278; Missing (in isoform 2)

3D Structural Models

Domain & Motif Annotations

Compositional Bias
233..243; Low complexity
Coiled Coil
153..179
Domain (FT)
47..271; Saposin B-type
Region
215..278; Disordered
Protein Families
Canopy family
Sequence Similarities
Belongs to the canopy family.
Clinical Relevance
Disease Involvement
Disease variantEpilepsy
Antibody