Protein detail

CCD32

Coiled-coil domain-containing protein 32

Protein symbol CCD32	UniProt ID Q9BV29	EVMP score 0.50
Frequency 2	Transmembrane count	Protein classification Disease related genesHuman disease related genesPredicted intracellular proteins

Basic Information

Protein Names

Coiled-coil domain-containing protein 32

Protein Class

Disease related genesHuman disease related genesPredicted intracellular proteins

Protein Function

Disease related genes
Human disease related genes:Congenital malformations:Congenital malformations of the nervous system
Predicted intracellular proteins

Ensembl

ENSG00000128891

Entrez Gene Symbol

CCDC32

Gene Synonym

C15orf57MGC20481

Gene Description

Coiled-coil domain containing 32

Chromosome

Position

40528683-40565054

Frequency

EVMP Score

0.50

Fluorescence & Localization

Cell SpecificAdrenal medulla cellsSingle-Nuclei Brain Specificendothelial cell

Function & Pathway

Protein Function

Disease related genes
Human disease related genes:Congenital malformations:Congenital malformations of the nervous system
Predicted intracellular proteins

Cellular Component

GO:0005905 clathrin-coated pit

Molecular Function

GO:0005515 protein binding

Biological Process

Mediation Categories

Adhesion and uptake mediation

Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

2 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
intracellular	intracellular	ComPPI	No	No	No	No	No
intracellular	intracellular	OmniPath	No	No	No	No	No

Regulatory Interaction Network

0 records.

Protein Complex Composition

1 record.

Component Name	Component Gene Symbols	Component UniProt ID	Stoichiometry	Database	Database IDs	References
	AAGAB AP1S3 ASAH1 CCDC32	Q13510 Q6PD74 Q96PC3 Q9BV29	0:0:0:0	hu.MAP2

Isolation & Detection Technology

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential UltracentrifugationDensity Gradient CentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion Chromatography	Mass spectrometry	6	41216884 32468033 37786918 34817906 28986585 38321535

Sequence, Structure & Domains

Sequences

Length

185

Mass

20,656

Sequence

MKMFESADSTATRSGQDLWAEICSCLPNPEQEDGANNAFSDSFVDSCPEGEGQREVADFAVQPAVKPWAPLQDSEVYLASLEKKLRRIKGLNQEVTSKDMLRTLAQAKKECWDRFLQEKLASEFFVDGLDSDESTLEHFKRWLQPDKVAVSTEEVQYLIPPESQVEKPVAEDEPAAGDKPAAAEQ

Alternative Products

Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q9BV29-1; Sequence=Displayed; Name=2; IsoId=Q9BV29-2; Sequence=VSP_027485; Name=3; IsoId=Q9BV29-3; Sequence=VSP_027486, VSP_027487

Alternative Sequence

1; M -> MRGSGLRFQM (in isoform 2); 134; S -> R (in isoform 3); 135..185; Missing (in isoform 3)

3D Structural Models

Domain & Motif Annotations

Coiled Coil

78..98

Region

159..185; Disordered

Clinical Relevance

Disease Involvement

Ciliopathy

Antibody

HPA041360 HPA041688

Interaction Protein

ENSG00000042753

Interaction Count

Interaction Dataset

biogrid_opencell