Protein detail
TM2D2
TM2 domain-containing protein 2 (Beta-amyloid-binding protein-like protein 1) (BBP-like protein 1)
Protein symbol TM2D2 | UniProt ID | EVMP score 0.50 |
Frequency 4 | Transmembrane count 2 | Protein classification Predicted intracellular proteinsPredicted membrane proteins |
Basic Information
Protein Names
TM2 domain-containing protein 2 (Beta-amyloid-binding protein-like protein 1) (BBP-like protein 1)
Protein Class
Predicted intracellular proteinsPredicted membrane proteins
Protein Function
Predicted intracellular proteins
Transmembrane
145..165; Helical; 183..203; Helical
Transmembrane Count
2
Ensembl
Entrez Gene Symbol
Gene Synonym
BLP1
Gene Description
TM2 domain containing 2
Chromosome
8
Position
38988808-38996824
Frequency
4
EVMP Score
0.50
Fluorescence & Localization
Tissue SpecificintestineCell SpecificEndometrial glandular cellsSingle-Nuclei Brain Specifichippocampal dentate gyrus
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
8 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
| transmembrane | transmembrane | UniProt_location | No | No | No | No | No |
| transmembrane | transmembrane | UniProt_topology | No | No | No | No | No |
| transmembrane | transmembrane | UniProt_keyword | No | No | No | No | No |
| transmembrane | transmembrane | Ramilowski_location | No | No | No | No | No |
| transmembrane | transmembrane | OmniPath | No | No | No | No | No |
| transmembrane | transmembrane_predicted | Phobius | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Size Exclusion Chromatography | Mass spectrometryMass spectrometry [LTQ-FT Ultra] | 1 | 34771645 |
Sequence, Structure & Domains
Sequences
Length
214
Mass
22,871
Sequence
MVLGGCPVSYLLLCGQAALLLGNLLLLHCVSRSHSQNATAEPELTSAGAAQPEGPGGAASWEYGDPHSPVILCSYLPDEFIECEDPVDHVGNATASQELGYGCLKFGGQAYSDVEHTSVQCHALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTVY
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9BX73-1; Sequence=Displayed; Name=2; IsoId=Q9BX73-2; Sequence=VSP_027495
Alternative Sequence
1..76; MVLGGCPVSYLLLCGQAALLLGNLLLLHCVSRSHSQNATAEPELTSAGAAQPEGPGGAASWEYGDPHSPVILCSYL -> MKKCLLPVLITCMQTAICKDRMMMIMILLVNYR (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Domain (FT)
147..195; TM2
Region
40..59; Disordered
Protein Families
TM2 family
Sequence Similarities
Belongs to the TM2 family.