Protein detail
TLR10
Toll-like receptor 10 (CD antigen CD290)
Entry name TLR10 | UniProt ID | EVMP score 0.50 |
Frequency 1 | Transmembrane count 1 | Protein classification |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Toll-like receptor 10 (CD antigen CD290)
Protein Function
- CD markers
- Predicted intracellular proteins
Transmembrane
577..597; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Frequency
1
EVMP Score
0.50
Fluorescence & Localization
Tissue SpecificbrainBrain Regional SpecificamygdalaCell SpecificAlveolar cells type 1Single-Nuclei Brain Specifichippocampal dentate gyrus
Function & Pathway
Protein Function
- CD markers
- Predicted intracellular proteins
Cellular Component
Molecular Function
Reactome
Mediation Categories
Clinical-translation mediationImmune mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
33 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| receptor | receptor | HGNC | No | Yes | No | Yes | No |
| receptor | receptor | HPMR | No | Yes | No | Yes | No |
| receptor | receptor | Surfaceome | No | Yes | No | Yes | No |
| toll_like | receptor | Almen2009 | No | Yes | No | Yes | No |
| toll | receptor | HPMR | No | Yes | No | Yes | No |
| til_toll | receptor | HPMR | No | Yes | No | Yes | No |
| toll | receptor | Surfaceome | No | Yes | No | Yes | No |
| receptor | receptor | OmniPath | No | Yes | No | Yes | No |
| extracellular | extracellular | HPMR | No | No | No | Yes | No |
| extracellular | extracellular | OmniPath | No | No | No | Yes | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Mass spectrometrySmall R sequencing (Illumi HiSeq 2000 (Solexa) | 0 |
Sequence, Structure & Domains
Sequences
Length
811
Mass
94,564
Sequence
MRLIRNIYIFCSIVMTAEGDAPELPEERELMTNCSNMSLRKVPADLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLDLSNNRLKSVTWYLLAGLRYLDLSFNDFDTMPICEEAGNMSHLEILGLSGAKIQKSDFQKIAHLHLNTVFLGFRTLPHYEEGSLPILNTTKLHIVLPMDTNFWVLLRDGIKTSKILEMTNIDGKSQFVSYEMQRNLSLENAKTSVLLLNKVDLLWDDLFLILQFVWHTSVEHFQIRNVTFGGKAYLDHNSFDYSNTVMRTIKLEHVHFRVFYIQQDKIYLLLTKMDIENLTISNAQMPHMLFPNYPTKFQYLNFANNILTDELFKRTIQLPHLKTLILNGNKLETLSLVSCFANNTPLEHLDLSQNLLQHKNDENCSWPETVVNMNLSYNKLSDSVFRCLPKSIQILDLNNNQIQTVPKETIHLMALRELNIAFNFLTDLPGCSHFSRLSVLNIEMNFILSPSLDFVQSCQEVKTLNAGRNPFRCTCELKNFIQLETYSEVMMVGWSDSYTCEYPLNLRGTRLKDVHLHELSCNTALLIVTIVVIMLVLGLAVAFCCLHFDLPWYLRMLGQCTQTWHRVRKTTQEQLKRNVRFHAFISYSEHDSLWVKNELIPNLEKEDGSILICLYESYFDPGKSISENIVSFIEKSYKSIFVLSPNFVQNEWCHYEFYFAHHNLFHENSDHIILILLEPIPFYCIPTRYHKLKALLEKKAYLEWPKDRRKCGLFWANLRAAINVNVLATREMYELQTFTELNEESRGSTISLMRTDCL
3D Structural Models
Turn
717..719
Helix
642..644; 645..650; 652..656; 668..671; 678..687; 698..703; 705..707; 709..712; 735..737; 743..750; 761..763; 764..775
Beta Strand
634..639; 689..696; 725..731; 754..756
3D Structure
X-ray crystallography (1)
Domain & Motif Annotations
Repeat
24..46; LRR 1; 49..70; LRR 2; 73..94; LRR 3; 97..118; LRR 4; 119..139; LRR 5; 143..166; LRR 6; 296..321; LRR 7; 325..348; LRR 8; 349..368; LRR 9; 373..394; LRR 10; 398..419; LRR 11; 422..442; LRR 12; 444..465; LRR 13; 467..488; LRR 14; 489..509; LRR 15
Domain (FT)
522..576; LRRCT; 632..775; TIR
Protein Families
Toll-like receptor family
Sequence Similarities
Belongs to the Toll-like receptor family.