Protein detail
CABP8
Calcium-binding protein 8 (CaBP8) (Calneuron I) (Calneuron-1)
Protein symbol CABP8 | UniProt ID | EVMP score 0.38 |
Frequency 1 | Transmembrane count 1 | Protein classification Predicted intracellular proteinsPredicted membrane proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Calcium-binding protein 8 (CaBP8) (Calneuron I) (Calneuron-1)
Protein Class
Predicted intracellular proteinsPredicted membrane proteins
Protein Function
Predicted intracellular proteins
Transmembrane
235..255; Helical; Anchor for type IV membrane protein
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym
CABP8
Gene Description
Calneuron 1
Chromosome
7
Position
71779491-72447151
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Tissue SpecificbrainCell SpecificAstrocytes
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Canonical Pathways
- M128 Pid tnf pathway
- M153 Pid p75 ntr pathway
Mediation Categories
Fusion and delivery mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
13 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | No | No |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | No | No |
| transmembrane | transmembrane_predicted | Phobius | No | No | No | No | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationDensity Gradient CentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion ChromatographyImmunoaffinity Capture | Mass spectrometryWestern blottingFlow cytometryMORPHELISA | 17 | 4121688439989284327954143816890639873726394090153481790638731868305502873370951039478498383215354009834631320591403116163045137133709510 |
Sequence, Structure & Domains
Sequences
Length
261
Mass
29,324
Sequence
MRLPEQPGEGKPENEKKGDGGALGGGEEPPRSQAPDFPTWEKMPFHHVTAGLLYKGNYLNRSLSAGSDSEQLANISVEELDEIREAFRVLDRDGNGFISKQELGMAMRSLGYMPSEVELAIIMQRLDMDGDGQVDFDEFMTILGPKLVSSEGRDGFLGNTIDSIFWQFDMQRITLEELKHILYHAFRDHLTMKDIENIIINEEESLNETSGNCQTEFEGVHSQKQNRQTCVRKSLICAFAMAFIISVMLIAANQILRSGME
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9BXU9-2; Sequence=Displayed; Name=2; IsoId=Q9BXU9-1; Sequence=VSP_060873
Alternative Sequence
1..42; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Compositional Bias
8..19; Basic and acidic residues
Domain (CC)
The C-terminal transmembrane domain (TMD) is necessary and sufficient for membrane targeting.
Domain (FT)
78..113; EF-hand 1; 114..149; EF-hand 2
Region
1..39; Disordered