Protein detail
NIBA1
Protein Niban 1 (Cell growth-inhibiting gene 39 protein) (Protein FAM129A)
Protein symbol NIBA1 | UniProt ID | EVMP score 0.63 |
Frequency 8 | Transmembrane count | Protein classification Cancer-related genesPredicted intracellular proteins |
Basic Information
Protein Names
Protein Niban 1 (Cell growth-inhibiting gene 39 protein) (Protein FAM129A)
Protein Class
Cancer-related genesPredicted intracellular proteins
Protein Function
- Cancer-related genes:Candidate cancer biomarkers
- Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
C1orf24FAM129AGIG39NIBAN
Gene Description
Niban apoptosis regulator 1
Chromosome
1
Position
184790724-184974508
Frequency
8
EVMP Score
0.63
Fluorescence & Localization
Tissue SpecificbrainCell SpecificBrain inhibitory neuronsSingle-Nuclei Brain Specificpericyte
Function & Pathway
Protein Function
- Cancer-related genes:Candidate cancer biomarkers
- Predicted intracellular proteins
Cellular Component
Molecular Function
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
1 record.
| Substrate Gene Symbol | Enzyme Gene Symbol | Enzyme UniProt ID | Residue Type | Residue Offset | Modification | Database | References |
|---|---|---|---|---|---|---|---|
| NIBAN1 | AKT1 | P31749 | S | 602 | phosphorylation | phosphoELM_MIMPPhosphoSite_MIMPMIMPHPRD_MIMPSIGNORProtMapperSIGNOR_ProtMapperPhosphoSitePhosphoSite_ProtMapper | SIGNOR:22510990ProtMapper:22510990 |
Ligand-Receptor Signaling
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
1 record.
| Source Protein Symbol | Source UniProt ID | Target Protein Symbol | Target UniProt ID | Is Directed | Is Stimulation | Is Inhibition | Database | References |
|---|---|---|---|---|---|---|---|---|
| AKT1 | P31749 | NIBA1 | Q9BZQ8 | Yes | No | No | phosphoELM_MIMPPhosphoSite_MIMPMIMPHPRD_MIMPiPTMnetSIGNORProtMapperSIGNOR_ProtMapperPhosphoSitePhosphoSite_ProtMapper | PhosphoSite:22510990SIGNOR:22510990ProtMapper:22510990 |
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Size Exclusion Chromatography | Mass spectrometryR Sequencing | 1 | 38343172 |
Sequence, Structure & Domains
Sequences
Length
928
Mass
103,135
Sequence
MGGSASSQLDEGKCAYIRGKTEAAIKNFSPYYSRQYSVAFCNHVRTEVEQQRDLTSQFLKTKPPLAPGTILYEAELSQFSEDIKKWKERYVVVKNDYAVESYENKEAYQRGAAPKCRILPAGGKVLTSEDEYNLLSDRHFPDPLASSEKENTQPFVVLPKEFPVYLWQPFFRHGYFCFHEAADQKRFSALLSDCVRHLNHDYMKQMTFEAQAFLEAVQFFRQEKGHYGSWEMITGDEIQILSNLVMEELLPTLQTDLLPKMKGKKNDRKRTWLGLLEEAYTLVQHQVSEGLSALKEECRALTKGLEGTIRSDMDQIVNSKNYLIGKIKAMVAQPAEKSCLESVQPFLASILEELMGPVSSGFSEVRVLFEKEVNEVSQNFQTTKDSVQLKEHLDRLMNLPLHSVKMEPCYTKVNLLHERLQDLKSRFRFPHIDLVVQRTQNYMQELMENAVFTFEQLLSPHLQGEASKTAVAIEKVKLRVLKQYDYDSSTIRKKIFQEALVQITLPTVQKALASTCKPELQKYEQFIFADHTNMIHVENVYEEILHQILLDETLKVIKEAAILKKHNLFEDNMALPSESVSSLTDLKPPTGSNQASPARRASAILPGVLGSETLSNEVFQESEEEKQPEVPSSLAKGESLSLPGPSPPPDGTEQVIISRVDDPVVNPVATEDTAGLPGTCSSELEFGGTLEDEEPAQEEPEPITASGSLKALRKLLTASVEVPVDSAPVMEEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEELGGFPEVGSPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQQEGCTLGSDPICLSESQVSEEQEEMGGQSSAAQATASVNAEEIKVARIHECQWVVEDAPNPDVLLSHKDDVKEGEGGQESFPELPSEE
3D Structural Models
Domain & Motif Annotations
Compositional Bias
580..596; Polar residues; 690..701; Acidic residues; 801..818; Low complexity; 825..834; Basic and acidic residues; 865..877; Low complexity; 905..915; Basic and acidic residues
Region
580..600; Disordered; 618..654; Disordered; 669..707; Disordered; 723..877; Disordered; 899..928; Disordered
Protein Families
Niban family
Sequence Similarities
Belongs to the Niban family.