Protein detail

SPC1L

Speriolin-like protein (Spermatogenesis and centriole-associated protein 1-like protein)

Entry name SPC1L	UniProt ID Q9H0A9	EVMP confidence score 0.38
Supporting publications (n) 1	Transmembrane count	Protein classification Predicted intracellular proteins

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information11

Protein Names

Speriolin-like protein (Spermatogenesis and centriole-associated protein 1-like protein)

Protein Class

Predicted intracellular proteins

Protein Function

Predicted intracellular proteins

Ensembl

ENSG00000160284

Entrez Gene Symbol

SPATC1L

Gene Synonym

C21orf56

Gene Description

Spermatogenesis and centriole associated 1 like

Chromosome

Position

46161148-46184476

Supporting publications (n)

EVMP confidence score

0.38

Fluorescence & Localization1

Cell SpecificPlatelets

Function & Pathway5

Protein Function

Predicted intracellular proteins

Cellular Component (3)

Molecular Function (4)

Biological Process (3)

Mediation Categories

Fusion and delivery mediation

Relations & Evidence6

Ligand-Receptor Signaling (4)

4 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
intracellular	intracellular	ComPPI	No	No	No	No	No
intracellular	intracellular	GO_Intercell	No	No	No	No	No
intracellular	intracellular	UniProt_location	No	No	No	No	No
intracellular	intracellular	OmniPath	No	No	No	No	No

Protein Complex Composition (1)

1 record.

Component Name	Component Gene Symbols	Component UniProt ID	Stoichiometry	Database	Database IDs	References
	ASPDH SPATC1L	A6ND91 Q9H0A9	0:0	hu.MAP

Isolation & Detection Technology (1)

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential UltracentrifugationSize Exclusion Chromatography	Western BlottingMass SpectrometryElisa	1	37204515

Sequence, Structure & Domains9

Sequences

Length

340

Mass

37,613

Sequence

MAEGGELMSRLLSENADLKKQVRLLKENQMLRRLLSQSCQEGGGHDLLPPRAHAYPEAGSPGSGVPDFGRFTSVADTPSQLQTSSLEDLLCSHAPLSSEDDTSPGCAAPSQAPFKAFLSPPEPHSHRGTDRKLSPLLSPLQDSLVDKTLLEPREMVRPKKVCFSESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTVANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAALRKLVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLFAW

Alternative Products

Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9H0A9-1; Sequence=Displayed; Name=2; IsoId=Q9H0A9-2; Sequence=VSP_039151

Alternative Sequence

1..154; Missing (in isoform 2)

Domain & Motif Annotations

Compositional Bias

123..133; Basic and acidic residues

Region

42..73; Disordered; 94..135; Disordered

Protein Families

Speriolin family

Sequence Similarities

Belongs to the speriolin family.

Clinical Relevance1

Antibody (2)

HPA019165 HPA029394

Supporting Publications1

PMID	Title	Abstract
37685904	Exosomal MicroRNA and Protein Profiles of Hepatitis B Virus-Related Hepatocellular Carcinoma Cells.	Extracellular vesicles, such as exosomes, play an important role in tumor development and metastasis, including regulation of HBV-related HCC.