Protein detail
SPC1L
Speriolin-like protein (Spermatogenesis and centriole-associated protein 1-like protein)
Entry name SPC1L | UniProt ID | EVMP confidence score 0.28 |
Supporting publications (n) 1 | Transmembrane count | Protein classification Predicted intracellular proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Speriolin-like protein (Spermatogenesis and centriole-associated protein 1-like protein)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
C21orf56
Gene Description
Spermatogenesis and centriole associated 1 like
Chromosome
21
Position
46161148-46184476
Supporting publications (n)
1
EVMP confidence score
0.28
Fluorescence & Localization
Cell SpecificPlatelets
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component (3)
Molecular Function (4)
Biological Process (3)
Mediation Categories
Fusion and delivery mediation
Relations & Evidence6
Ligand-Receptor Signaling (4)
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | |||||
| intracellular | intracellular | GO_Intercell | |||||
| intracellular | intracellular | UniProt_location | |||||
| intracellular | intracellular | OmniPath |
Protein Complex Composition (1)
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationSize Exclusion Chromatography | Western BlottingMass SpectrometryElisa | 1 | 37204515 |
Sequence, Structure & Domains
Sequences
Length
340
Mass
37,613
Sequence
MAEGGELMSRLLSENADLKKQVRLLKENQMLRRLLSQSCQEGGGHDLLPPRAHAYPEAGSPGSGVPDFGRFTSVADTPSQLQTSSLEDLLCSHAPLSSEDDTSPGCAAPSQAPFKAFLSPPEPHSHRGTDRKLSPLLSPLQDSLVDKTLLEPREMVRPKKVCFSESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTVANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAALRKLVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLFAW
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9H0A9-1; Sequence=Displayed; Name=2; IsoId=Q9H0A9-2; Sequence=VSP_039151
Alternative Sequence
1..154; Missing (in isoform 2)
Domain & Motif Annotations
Compositional Bias
123..133; Basic and acidic residues
Region
42..73; Disordered; 94..135; Disordered
Protein Families
Speriolin family
Sequence Similarities
Belongs to the speriolin family.
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 37685904 | Exosomal MicroRNA and Protein Profiles of Hepatitis B Virus-Related Hepatocellular Carcinoma Cells. | Extracellular vesicles, such as exosomes, play an important role in tumor development and metastasis, including regulation of HBV-related HCC. |