Protein detail

ENKD1

Enkurin domain-containing protein 1

Entry name
ENKD1
UniProt ID
EVMP score
0.38
Frequency
2
Transmembrane count
Protein classification
Predicted intracellular proteins
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Enkurin domain-containing protein 1
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Entrez Gene Symbol
Gene Synonym
C16orf48DKFZP434A1319FBB11
Gene Description
Enkurin domain containing 1
Chromosome
16
Position
67662945-67667265
Frequency
2
EVMP Score
0.38
Fluorescence & Localization
ENKD1 fluorescence
Cell SpecificBergmann gliaBlood Cell Specificbasophil
Function & Pathway
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

4 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularGO_IntercellNoNoNoNoNo
intracellularintracellularUniProt_locationNoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo

Regulatory Interaction Network

0 records.

Protein Complex Composition

1 record.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
ENKD1MAGEC1SUV39H1O43463O60732Q9H0I20:0:0hu.MAP2

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion ChromatographyWestern blottingELISA441227296387318684078452937922300
Sequence, Structure & Domains

Sequences

Length
346
Mass
38,759
Sequence
MCEGPSRISGPIPPDPTLCPDNYRRPTSAQGRLEGNALKLDLLTSDRALDTTAPRGPCIGPGAGEILERGQRGVGDVLLQLEGISLGPGASLKRKDPKDHEKENLRRIREIQKRFREQERSREQGQPRPLKALWRSPKYDKVESRVKAQLQEPGPASGTESAHFLRAHSRCGPGLPPPHVSSPQPTPPGPEAKEPGLGVDFIRHNARAAKRAPRRHSCSLQVLAQVLEQQRQAQEHYNATQKGHVPHYLLERRDLWRREAEARKQSQPDPAMPPGHTRMPENQRLETLTKLLQSQSQLLRELVLLPAGADSLRAQSHRAELDRKLVQVEEAIKIFSRPKVFVKMDD
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9H0I2-1; Sequence=Displayed; Name=2; IsoId=Q9H0I2-2; Sequence=VSP_021904, VSP_021905
Alternative Sequence
1..118; Missing (in isoform 2); 119..149; ERSREQGQPRPLKALWRSPKYDKVESRVKAQ -> MDAKVRRAKMARVLQLEPQTSACLLSLLCPA (in isoform 2)

3D Structural Models

Domain & Motif Annotations

Compositional Bias
114..125; Basic and acidic residues; 174..190; Pro residues
Domain (FT)
251..343; Enkurin
Region
1..35; Disordered; 91..171; Required for binding to microtubules; 114..137; Disordered; 167..197; Disordered; 260..280; Disordered
Clinical Relevance
Interaction Protein
ENSG00000075702ENSG00000108953ENSG00000112559ENSG00000114107ENSG00000240694
Interaction Count
5
Interaction Dataset
intact_biogrid