Protein detail
TM222
Transmembrane protein 222
Entry name TM222 | UniProt ID | EVMP score 0.50 |
Frequency 1 | Transmembrane count 3 | Protein classification Disease related genesHuman disease related genesPredicted membrane proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Transmembrane protein 222
Protein Class
Disease related genesHuman disease related genesPredicted membrane proteins
Protein Function
- Disease related genes
- Human disease related genes:Congenital malformations:Congenital malformations of the nervous system
Transmembrane
56..76; Helical; 165..185; Helical; 187..207; Helical
Transmembrane Count
3
Ensembl
Entrez Gene Symbol
Gene Synonym
C1orf160DKFZP564D0478
Gene Description
Transmembrane protein 222
Chromosome
1
Position
27322145-27336400
Frequency
1
EVMP Score
0.50
Fluorescence & Localization
Tissue Specificskeletal muscleCell SpecificCardiomyocytes
Function & Pathway
Protein Function
- Disease related genes
- Human disease related genes:Congenital malformations:Congenital malformations of the nervous system
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
10 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
| transmembrane | transmembrane | UniProt_location | No | No | No | No | No |
| transmembrane | transmembrane | UniProt_topology | No | No | No | No | No |
| transmembrane | transmembrane | UniProt_keyword | No | No | No | No | No |
| transmembrane_predicted | transmembrane | OmniPath | No | No | No | No | No |
| transmembrane | transmembrane | Ramilowski_location | No | No | No | No | No |
| transmembrane | transmembrane | OmniPath | No | No | No | No | No |
| transmembrane | transmembrane_predicted | Phobius | No | No | No | No | No |
| transmembrane_sosui | transmembrane_predicted | Almen2009 | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Sequence, Structure & Domains
Sequences
Length
208
Mass
23,230
Sequence
MAEAEGSSLLLLPPPPPPPRMAEVEAPTAAETDMKQYQGSGGVAMDVERSRFPYCVVWTPIPVLTWFFPIIGHMGICTSTGVIRDFAGPYFVSEDNMAFGKPAKYWKLDPAQVYASGPNAWDTAVHDASEEYKHRMHNLCCDNCHSHVALALNLMRYNNSTNWNMVTLCFFCLLYGKYVSVGAFVKTWLPFILLLGIILTVSLVFNLR
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9H0R3-1; Sequence=Displayed; Name=2; IsoId=Q9H0R3-2; Sequence=VSP_020090
Alternative Sequence
1..96; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Region
1..26; Disordered