Protein detail
CXL16
C-X-C motif chemokine 16 (Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein) (SR-PSOX) (Small-inducible cytokine B16) (Transmembrane chemokine CXCL16)
Entry name CXL16 | UniProt ID | EVMP confidence score 0.53 |
Supporting publications (n) 2 | Transmembrane count 1 | Protein classification Predicted intracellular proteinsPredicted membrane proteinsPredicted secreted proteinsTransporters |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
C-X-C motif chemokine 16 (Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein) (SR-PSOX) (Small-inducible cytokine B16) (Transmembrane chemokine CXCL16)
Protein Class (4)
Predicted intracellular proteinsPredicted membrane proteinsPredicted secreted proteinsTransporters
Protein Function (3)
- Predicted secreted proteins
- Transporters
- Predicted intracellular proteins
Transmembrane
206..226; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym (3)
CXCLG16SR-PSOXSRPSOX
Gene Description
C-X-C motif chemokine ligand 16
Chromosome
17
Position
4733533-4739928
Supporting publications (n)
2
EVMP confidence score
0.53
Fluorescence & Localization
Tissue SpecifictestisCell SpecificEarly spermatids
Function & Pathway
Protein Function (3)
- Predicted secreted proteins
- Transporters
- Predicted intracellular proteins
Cellular Component (4)
Molecular Function (3)
Biological Process (3)
Reactome (6)
Mediation Categories (3)
Adhesion and uptake mediationImmune mediationReceptor-signaling mediation
Relations & Evidence42
Ligand-Receptor Signaling (41)
41 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| secreted | secreted | connectomeDB2020 | Yes | Yes | |||
| secreted | secreted | Baccin2019 | Yes | Yes | |||
| secreted | secreted | Cellinker | Yes | Yes | |||
| secreted | secreted | OmniPath | Yes | Yes | |||
| cell_surface | cell_surface | Surfaceome | Yes | Yes | |||
| cell_surface | cell_surface | Baccin2019 | Yes | Yes | |||
| cell_surface | cell_surface | OmniPath | Yes | Yes | |||
| receptor | receptor | CellCellInteractions | Yes | Yes | Yes | ||
| scavenger | receptor | HGNC | Yes | Yes | Yes | ||
| receptor | receptor | HGNC | Yes | Yes | Yes |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion Chromatography | Mass spectrometry | 1 | 12872166 |
Sequence, Structure & Domains
Sequences
Length
254
Mass
27,579
Sequence
MGRDLRPGSRVLLLLLLLLLVYLTQPGNGNEGSVTGSCYCGKRISSDSPPSVQFMNRLRKHLRAYHRCLYYTRFQLLSWSVCGGNKDPWVQELMSCLDLKECGHAYSGIVAHQKHLLPTSPPISQASEGASSDIHTPAQMLLSTLQSTQRPTLPVGSLSSDKELTRPNETTIHTAGHSLAAGPEAGENQKQPEKNAGPTARTSATVPVLCLLAIIFILTAALSYVLCKRRRGQSPQSSPDLPVHYIPVAPDSNT
Domain & Motif Annotations
Region
32..107; Chemokine; 146..165; Disordered; 178..200; Disordered; 231..254; Disordered
Protein Families
Intercrine alpha (chemokine CxC) family
Sequence Similarities
Belongs to the intercrine alpha (chemokine CxC) family.
Supporting Publications2
| PMID | Title | Related sentences |
|---|---|---|
| 26884841 | Exosomes mediated pentose phosphate pathway in ovarian cancer metastasis: a proteomics analysis. | No related sentences available |
| 38731868 | The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer. | No related sentences available |