Protein detail
MUC13
Mucin-13 (MUC-13) (Down-regulated in colon cancer 1)
Entry name MUC13 | UniProt ID | EVMP confidence score 0.35 |
Supporting publications (n) 0 | Transmembrane count 1 | Protein classification Predicted membrane proteinsPredicted secreted proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Mucin-13 (MUC-13) (Down-regulated in colon cancer 1)
Protein Class (2)
Predicted membrane proteinsPredicted secreted proteins
Protein Function
Predicted secreted proteins
Transmembrane
422..442; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym
DRCC1
Gene Description
Mucin 13, cell surface associated
Chromosome
3
Position
124905442-124953819
Supporting publications (n)
0
EVMP confidence score
0.35
Fluorescence & Localization
Tissue Specificbrain
Function & Pathway
Protein Function
Predicted secreted proteins
Cellular Component (5)
Molecular Function
Biological Process (3)
Reactome (17)
- R-hsa-5621481 c type lectin receptors clrs
- R-hsa-5621480 dectin 2 family
- R-hsa-5083632 defective c1galt1c1 causes tnps
- R-hsa-5083625 defective galnt3 causes hftc
- R-hsa-3906995 diseases associated with o glycosylation of proteins
- R-hsa-3781865 diseases of glycosylation
- R-hsa-5668914 diseases of metabolism
- R-hsa-168249 innate immune system
- R-hsa-5173105 o linked glycosylation
- R-hsa-913709 o linked glycosylation of mucins
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Mediation Categories (5)
Clinical-translation mediationFusion and delivery mediationImmune mediationMetabolism mediationReceptor-signaling mediation
Relations & Evidence28
Ligand-Receptor Signaling (27)
27 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| ecm | ecm | MatrixDB | Yes | Yes | Yes | ||
| ecm | ecm | OmniPath | Yes | Yes | Yes | ||
| intracellular | intracellular | ComPPI | Yes | Yes | |||
| intracellular | intracellular | GO_Intercell | Yes | Yes | |||
| intracellular | intracellular | OmniPath | Yes | Yes | |||
| transmembrane | transmembrane | UniProt_location | Yes | Yes | |||
| transmembrane | transmembrane | UniProt_topology | Yes | Yes | |||
| transmembrane | transmembrane | UniProt_keyword | Yes | Yes | |||
| transmembrane | transmembrane | LOCATE | Yes | Yes | |||
| transmembrane | transmembrane | Ramilowski_location | Yes | Yes |
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Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationSize Exclusion Chromatography | Mass spectrometry | 1 | 34889606 |
Sequence, Structure & Domains
Sequences
Length
512
Mass
54,604
Sequence
MKAIIHLTLLALLSVNTATNQGNSADAVTTTETATSGPTVAAADTTETNFPETASTTANTPSFPTATSPAPPIISTHSSSTIPTPAPPIISTHSSSTIPIPTAADSESTTNVNSLATSDIITASSPNDGLITMVPSETQSNNEMSPTTEDNQSSGPPTGTALLETSTLNSTGPSNPCQDDPCADNSLCVKLHNTSFCLCLEGYYYNSSTCKKGKVFPGKISVTVSETFDPEEKHSMAYQDLHSEITSLFKDVFGTSVYGQTVILTVSTSLSPRSEMRADDKFVNVTIVTILAETTSDNEKTVTEKINKAIRSSSSNFLNYDLTLRCDYYGCNQTADDCLNGLACDCKSDLQRPNPQSPFCVASSLKCPDACNAQHKQCLIKKSGGAPECACVPGYQEDANGNCQKCAFGYSGLDCKDKFQLILTIVGTIAGIVILSMIIALIVTARSNNKTKHIEEENLIDEDFQNLKLRSTGFTNLGAEGSVFPKVRITASRDSQMQNPYSRHSSMPRPDY
Domain & Motif Annotations
Compositional Bias
22..38; Polar residues; 53..67; Low complexity; 135..176; Polar residues; 493..505; Polar residues
Domain (FT)
173..211; EGF-like 1; 212..336; SEA; 322..361; EGF-like 2; 363..404; EGF-like 3
Region
22..67; Disordered; 133..176; Disordered; 493..512; Disordered