Protein detail
RHOJ
Rho-related GTP-binding protein RhoJ (Ras-like protein family member 7B) (Tc10-like GTP-binding protein)
Protein symbol RHOJ | UniProt ID | EVMP score 0.50 |
Frequency 2 | Transmembrane count | Protein classification Predicted intracellular proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Rho-related GTP-binding protein RhoJ (Ras-like protein family member 7B) (Tc10-like GTP-binding protein)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
ARHJFLJ14445RASL7BTCL
Gene Description
Ras homolog family member J
Chromosome
14
Position
63204114-63293508
Frequency
2
EVMP Score
0.50
Fluorescence & Localization
Cell SpecificAstrocytesSingle-Nuclei Brain SpecificBergmann glia
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Reactome
Mediation Categories
Fusion and delivery mediationReceptor-signaling mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
5 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | No | No |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationSize Exclusion Chromatography | Mass spectrometry | 1 | 34889606 |
Sequence, Structure & Domains
Sequences
Length
214
Mass
23,821
Sequence
MNCKEGTDSSCGCRGNDEKKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPHVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAILTIFHPKKKKKRCSEGHSCCSII
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9H4E5-1; Sequence=Displayed; Name=2; IsoId=Q9H4E5-2; Sequence=VSP_007231
Alternative Sequence
113..134; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Motif
50..58; Effector region
Protein Families
- Small GTPase superfamily
- Rho family
Sequence Similarities
Belongs to the small GTPase superfamily. Rho family.
Clinical Relevance
Antibody
Interaction Protein
ENSG00000106299ENSG00000124171ENSG00000128283ENSG00000149269ENSG00000180370
Interaction Count
5
Interaction Dataset
intact_biogrid