Protein detail

IGFR1

IGF-like family receptor 1 (Transmembrane protein 149) (U2 small nuclear RNA auxiliary factor 1-like 4)

Protein symbol
IGFR1
UniProt ID
EVMP score
0.50
Frequency
4
Transmembrane count
1
Protein classification
Predicted intracellular proteinsPredicted membrane proteins
Basic Information
Protein Names
IGF-like family receptor 1 (Transmembrane protein 149) (U2 small nuclear RNA auxiliary factor 1-like 4)
Protein Class
Predicted intracellular proteinsPredicted membrane proteins
Protein Function
Predicted intracellular proteins
Transmembrane
164..184; Helical
Transmembrane Count
1
Entrez Gene Symbol
Gene Synonym
FLJ22573TMEM149U2AF1L4
Gene Description
IGF like family receptor 1
Chromosome
19
Position
35738801-35742453
Frequency
4
EVMP Score
0.50
Fluorescence & Localization
Cell SpecificAstrocytes
Function & Pathway
Protein Function
Predicted intracellular proteins
Molecular Function
Canonical Pathways
M58 Pid ar pathway
Mediation Categories
Other mediation
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

36 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
receptorreceptorCellPhoneDBNoYesNoYesNo
receptorreceptorCellChatDBNoYesNoYesNo
receptorreceptorCellTalkDBNoYesNoYesNo
receptorreceptorRamilowski2015NoYesNoYesNo
receptorreceptorLRdbNoYesNoYesNo
receptorreceptorOmniPathNoYesNoYesNo
intracellularintracellularGO_IntercellNoNoNoYesNo
intracellularintracellularOmniPathNoNoNoYesNo
cell_adhesioncell_adhesionCellinkerYesYesNoYesNo
adhesionadhesionOmniPathYesYesNoYesNo
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Regulatory Interaction Network

0 records.

Protein Complex Composition

0 records.

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyImmunoaffinity CaptureMass spectrometry738113368373224754018949732854315413079683614683438207106
Sequence, Structure & Domains

Sequences

Length
355
Mass
37,895
Sequence
MGPGRCLLTALLLLALAPPPEASQYCGRLEYWNPDNKCCSSCLQRFGPPPCPDYEFRENCGLNDHGDFVTPPFRKCSSGQCNPDGAELCSPCGGGAVTPTPAAGGGRTPWRCRERPVPAKGHCPLTPGNPGAPSSQERSSPASSIAWRTPEPVPQQAWPNFLPLVVLVLLLTLAVIAILLFILLWHLCWPKEKADPYPYPGLVCGVPNTHTPSSSHLSSPGALETGDTWKEASLLPLLSRELSSLASQPLSRLLDELEVLEELIVLLDPEPGPGGGMAHGTTRHLAARYGLPAAWSTFAYSLRPSRSPLRALIEMVVAREPSASLGQLGTHLAQLGRADALRVLSKLGSSGVCWA
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9H665-1; Sequence=Displayed; Name=2; IsoId=Q9H665-2; Sequence=VSP_026145
Alternative Sequence
53..240; Missing (in isoform 2)

3D Structural Models

Domain & Motif Annotations

Compositional Bias
132..144; Low complexity
Region
120..147; Disordered
Clinical Relevance