Protein detail
TASP1
Threonine aspartase 1 (Taspase-1) (EC 3.4.25.-) [Cleaved into: Threonine aspartase subunit alpha; Threonine aspartase subunit beta]
Entry name TASP1 | UniProt ID | EVMP score 0.38 |
Frequency 2 | Transmembrane count | Protein classification Disease related genesPredicted intracellular proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Threonine aspartase 1 (Taspase-1) (EC 3.4.25.-) [Cleaved into: Threonine aspartase subunit alpha; Threonine aspartase subunit beta]
Protein Class
Disease related genesPredicted intracellular proteins
Protein Function
- Disease related genes
- Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
C20orf13dJ585I14.2FLJ20212
Gene Description
Taspase 1
Chromosome
20
Position
13389392-13638932
Frequency
2
EVMP Score
0.38
Fluorescence & Localization
Cell SpecificAstrocytes
Function & Pathway
Protein Function
- Disease related genes
- Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Reactome
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
6 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| receptor | receptor | OmniPath | No | Yes | No | No | No |
| intracellular | intracellular | LOCATE | No | No | No | No | No |
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
| receptor | receptor | scConnect | No | Yes | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Mass spectrometry；RNA Sequencing；Flow cytometry | 1 | 41307968 |
Sequence, Structure & Domains
Sequences
Length
420
Mass
44,455
Sequence
MTMEKGMSSGEGLPSRSSQVSAGKITAKELETKQSYKEKRGGFVLVHAGAGYHSESKAKEYKHVCKRACQKAIEKLQAGALATDAVTAALVELEDSPFTNAGMGSNLNLLGEIECDASIMDGKSLNFGAVGALSGIKNPVSVANRLLCEGQKGKLSAGRIPPCFLVGEGAYRWAVDHGIPSCPPNIMTTRFSLAAFKRNKRKLELAERVDTDFMQLKKRRQSSEKENDSGTLDTVGAVVVDHEGNVAAAVSSGGLALKHPGRVGQAALYGCGCWAENTGAHNPYSTAVSTSGCGEHLVRTILARECSHALQAEDAHQALLETMQNKFISSPFLASEDGVLGGVIVLRSCRCSAEPDSSQNKQTLLVEFLWSHTTESMCVGYMSAQDGKAKTHISRLPPGAVAGQSVAIEGGVCRLESPVN
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q9H6P5-1; Sequence=Displayed; Name=2; IsoId=Q9H6P5-2; Sequence=VSP_056327, VSP_056328; Name=3; IsoId=Q9H6P5-3; Sequence=VSP_056533, VSP_056534
Alternative Sequence
95..129; DSPFTNAGMGSNLNLLGEIECDASIMDGKSLNFGA -> VYTHSYTSWSCIQPSIHVLLVKRQRKSPLPRISTF (in isoform 2); 96..145; SPFTNAGMGSNLNLLGEIECDASIMDGKSLNFGAVGALSGIKNPVSVANR -> VESILCAPYWLENVHMLYKLRMLTKPCWRLCKTSLSVHLSLPVKMACLAE (in isoform 3); 130..420; Missing (in isoform 2); 146..420; Missing (in isoform 3)
3D Structural Models
Turn
122..124; 152..154; 221..225; 269..271; 326..329; 384..386; 402..404
Helix
57..77; 82..95; 139..151; 167..176; 184..187; 190..204; 265..267; 294..299; 302..309; 315..325; 331..333
Beta Strand
42..52; 99..102; 115..121; 127..133; 135..137; 157..160; 163..166; 235..241; 246..252; 272..276; 282..292; 341..348; 365..383; 390..395; 407..414
3D Structure
X-ray crystallography (9)
Domain & Motif Annotations
Region
1..23; Disordered
Protein Families
Ntn-hydrolase family
Sequence Similarities
Belongs to the Ntn-hydrolase family.