Protein detail

PPIP2

Proline-serine-threonine phosphatase-interacting protein 2 (PEST phosphatase-interacting protein 2)

Entry name
PPIP2
UniProt ID
Q9H939
EVMP confidence score
0.40
Supporting publications (n)
1
Transmembrane count
Protein classification
Predicted intracellular proteins
Basic Information
Protein Names
Proline-serine-threonine phosphatase-interacting protein 2 (PEST phosphatase-interacting protein 2)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
ENSG00000152229
Entrez Gene Symbol
PSTPIP2
Gene Description
Proline-serine-threonine phosphatase interacting protein 2
Chromosome
18
Position
45983536-46072272
Supporting publications (n)
1
EVMP confidence score
0.40
Fluorescence & Localization
Tissue SpecificbrainCell SpecificAstrocytes
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component (4)
Molecular Function
GO:0051015 actin filament binding
Biological Process (3)
Mediation Categories
Fusion and delivery mediation
Relations & Evidence7

Ligand-Receptor Signaling (6)

6 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPI
intracellularintracellularGO_Intercell
intracellularintracellularUniProt_location
intracellularintracellularOmniPath
fbar_actin_dynamics_endocytosisintracellular_intercellular_relatedHGNCYes
intracellular_intercellular_relatedintracellular_intercellular_relatedOmniPathYes

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyMass spectrometry52898658527894104306466163832153533709510
Sequence, Structure & Domains

Sequences

Length
334
Mass
38,858
Sequence
MTRSLFKGNFWSADILSTIGYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTELIMDAIHKQKSLQFKKTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQQCVTSDEMYEQVRKSLEMCSIQRDIEYFVNQRKTGQIPPAPIMYENFYSSQKNAVPAGKATGPNLARRGPLPIPKSSPDDPNYSLVDDYSLLYQ
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9H939-1; Sequence=Displayed; Name=2; IsoId=Q9H939-2; Sequence=VSP_004070
Alternative Sequence
248..334; MYEQVRKSLEMCSIQRDIEYFVNQRKTGQIPPAPIMYENFYSSQKNAVPAGKATGPNLARRGPLPIPKSSPDDPNYSLVDDYSLLYQ -> HPSCMRISTPPRRMQSQQERLQGLTWQGEDPSQFLKAHQMIPITLWLMTTVCSISKINETRAFSG (in isoform 2)

Domain & Motif Annotations

Coiled Coil
66..166
Domain (FT)
4..264; F-BAR
Region
295..322; Disordered
Clinical Relevance
Antibody
HPA040944
Supporting Publications1
PMIDTitleRelated sentences
37886648Pathological mechanisms of type 1 diabetes in children: investigation of the exosomal protein expression profile.No related sentences available