Protein detail

JMJD4

2-oxoglutarate and iron-dependent oxygenase JMJD4 (EC 1.14.11.-) (JmjC domain-containing protein 4) (Jumonji domain-containing protein 4) (Lysyl-hydroxylase JMJD4)

Protein symbol
JMJD4
UniProt ID
EVMP score
0.38
Frequency
1
Transmembrane count
Protein classification
Predicted intracellular proteins
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
2-oxoglutarate and iron-dependent oxygenase JMJD4 (EC 1.14.11.-) (JmjC domain-containing protein 4) (Jumonji domain-containing protein 4) (Lysyl-hydroxylase JMJD4)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Entrez Gene Symbol
Gene Synonym
FLJ12517
Gene Description
Jumonji domain containing 4
Chromosome
1
Position
227730425-227735411
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Tissue SpecifickidneyCell SpecificPodocytesSingle-Nuclei Brain Specificendothelial cell
Function & Pathway
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

4 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularGO_IntercellNoNoNoNoNo
intracellularintracellularUniProt_locationNoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo

Regulatory Interaction Network

0 records.

Protein Complex Composition

1 record.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
HCCSJMJD4PHF23SNX20P53701Q7Z614Q9BUL5Q9H9V90:0:0:0hu.MAP2

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion ChromatographyWestern blottingELISA438731868337292552210607137686366
Sequence, Structure & Domains

Sequences

Length
417
Mass
47,425
Sequence
MDRETRALADSHFRGLGVDVPGVGQAPGRVAFVSEPGAFSYADFVRGFLLPNLPCVFSSAFTQGWGSRRRWVTPAGRPDFDHLLRTYGDVVVPVANCGVQEYNSNPKEHMTLRDYITYWKEYIQAGYSSPRGCLYLKDWHLCRDFPVEDVFTLPVYFSSDWLNEFWDALDVDDYRFVYAGPAGSWSPFHADIFRSFSWSVNVCGRKKWLLFPPGQEEALRDRHGNLPYDVTSPALCDTHLHPRNQLAGPPLEITQEAGEMVFVPSGWHHQVHNLDDTISINHNWVNGFNLANMWRFLQQELCAVQEEVSEWRDSMPDWHHHCQVIMRSCSGINFEEFYHFLKVIAEKRLLVLREAAAEDGAGLGFEQAAFDVGRITEVLASLVAHPDFQRVDTSAFSPQPKELLQQLREAVDAAAAP
Alternative Products
Event=Alternative splicing, Alternative initiation; Named isoforms=3; Name=3; IsoId=Q9H9V9-3; Sequence=Displayed; Name=1; IsoId=Q9H9V9-1; Sequence=VSP_062164; Name=2; IsoId=Q9H9V9-2; Sequence=VSP_062165
Alternative Sequence
1; M -> MRAGPEPQALAGQKRGALRLLVPRLVLTVSAPAEVRRRVLRPVLSWM (in isoform 1); 308..323; Missing (in isoform 2)

3D Structural Models

Domain & Motif Annotations

Domain (FT)
142..301; JmjC
Protein Families
JMJD6 family
Sequence Similarities
Belongs to the JMJD6 family.
Clinical Relevance