Protein detail

CEP15

Centrosomal protein 15 (Centrosomal protein 15 kDa)

Entry name CEP15	UniProt ID Q9HBI5	EVMP confidence score 0.38
Supporting publications (n) 1	Transmembrane count	Protein classification Predicted intracellular proteins

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information11

Protein Names

Centrosomal protein 15 (Centrosomal protein 15 kDa)

Protein Class

Predicted intracellular proteins

Protein Function

Predicted intracellular proteins

Ensembl

ENSG00000114405

Entrez Gene Symbol

CEP15

Gene Synonym

HT021

Gene Description

Chromosome 3 open reading frame 14

Chromosome

Position

62319015-62336213

Supporting publications (n)

EVMP confidence score

0.38

Fluorescence & Localization3

Cell SpecificAdipocytesBlood Cell SpecificneutrophilBlood Lineage Specificgranulocytes

Function & Pathway4

Protein Function

Predicted intracellular proteins

Cellular Component

GO:0005929 cilium

Biological Process (3)

Mediation Categories

Other mediation

Relations & Evidence6

Ligand-Receptor Signaling (2)

2 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
intracellular	intracellular	ComPPI	No	No	No	No	No
intracellular	intracellular	OmniPath	No	No	No	No	No

Protein Complex Composition (3)

3 records.

Component Name	Component Gene Symbols	Component UniProt ID	Stoichiometry	Database	Database IDs	References
CEP152-PLK4 complex	CEP152 PLK4	O00444 O94986	2:1	ComplexPortalPDB	PDB:4n7vPDB:4N7V	14755292
	CEP152	O94986	4	PDB	PDB:6csv
	CEP152 CEP63	O94986 Q96MT8	2:2	hu.MAPPDB	PDB:6csu

Isolation & Detection Technology (1)

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential Ultracentrifugation	Mass spectrometryFlow cytometryMORPH	1	24069378

Sequence, Structure & Domains3

Sequences

Length

128

Mass

15,007

Sequence

MTSLFAQEIRLSKRHEEIVSQRLMLLQQMENKLGDQHTEKASQLQTVETAFKRNLSLLKDIEAAEKSLQTRIHPLPRPEVVSLETRYWASVEEYIPKWEQFLLGRAPYPFAVENQNEAENTIQNEAQR

Clinical Relevance4

Antibody

HPA048286

Interaction Protein

ENSG00000121289

Interaction Count

Interaction Dataset

biogrid_bioplex

Supporting Publications1

PMID	Title	Abstract
23260141	Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration.	In orthotopic mouse models of breast cancer, coinjection of BCCs with fibroblasts dramatically enhances metastasis that is dependent on PCP signaling in BCCs and the exosome component, Cd81 in fibroblasts.