Protein detail

APMAP

Adipocyte plasma membrane-associated protein (Protein BSCv)

Entry name APMAP	UniProt ID Q9HDC9	EVMP confidence score 0.50
Supporting publications (n) 2	Transmembrane count 1	Protein classification Plasma proteinsPredicted intracellular proteinsPredicted membrane proteins

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information13

Protein Names

Adipocyte plasma membrane-associated protein (Protein BSCv)

Protein Class (3)

Plasma proteinsPredicted intracellular proteinsPredicted membrane proteins

Protein Function

Predicted intracellular proteins

Transmembrane

41..61; Helical; Signal-anchor for type II membrane protein

Transmembrane Count

Ensembl

ENSG00000101474

Entrez Gene Symbol

APMAP

Gene Synonym (2)

BSCvC20orf3

Gene Description

Adipocyte plasma membrane associated protein

Chromosome

Position

24962925-24992751

Supporting publications (n)

EVMP confidence score

0.50

Fluorescence & Localization3

Tissue SpecifickidneyCell SpecificRenal collecting duct principal cells

Function & Pathway5

Protein Function

Predicted intracellular proteins

Cellular Component (2)

Molecular Function (3)

Biological Process (3)

Mediation Categories

Other mediation

Relations & Evidence11

Ligand-Receptor Signaling (10)

10 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
transmembrane	transmembrane	UniProt_location	No	No	No	No	No
transmembrane	transmembrane	UniProt_topology	No	No	No	No	No
transmembrane	transmembrane	UniProt_keyword	No	No	No	No	No
transmembrane_predicted	transmembrane	OmniPath	No	No	No	No	No
transmembrane	transmembrane	TopDB	No	No	No	No	No
transmembrane	transmembrane	Ramilowski_location	No	No	No	No	No
transmembrane	transmembrane	OmniPath	No	No	No	No	No
transmembrane	transmembrane_predicted	Phobius	No	No	No	No	No
transmembrane_phobius	transmembrane_predicted	Almen2009	No	No	No	No	No
transmembrane_tmhmm	transmembrane_predicted	Almen2009	No	No	No	No	No

Isolation & Detection Technology (1)

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential UltracentrifugationSize Exclusion Chromatography	Mass spectrometryAntibody array	3	25776846 28240915 33017416

Sequence, Structure & Domains8

Sequences

Length

416

Mass

46,480

Sequence

MSEADGLRQRRPLRPQVVTDDDGQAPEAKDGSSFSGRVFRVTFLMLAVSLTVPLLGAMMLLESPIDPQPLSFKEPPLLLGVLHPNTKLRQAERLFENQLVGPESIAHIGDVMFTGTADGRVVKLENGEIETIARFGSGPCKTRDDEPVCGRPLGIRAGPNGTLFVADAYKGLFEVNPWKREVKLLLSSETPIEGKNMSFVNDLTVTQDGRKIYFTDSSSKWQRRDYLLLVMEGTDDGRLLEYDTVTREVKVLLDQLRFPNGVQLSPAEDFVLVAETTMARIRRVYVSGLMKGGADLFVENMPGFPDNIRPSSSGGYWVGMSTIRPNPGFSMLDFLSERPWIKRMIFKLFSQETVMKFVPRYSLVLELSDSGAFRRSLHDPDGLVATYISEVHEHDGHLYLGSFRSPFLCRLSLQAV

Alternative Products

Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9HDC9-1; Sequence=Displayed; Name=2; IsoId=Q9HDC9-2; Sequence=VSP_036992, VSP_036993

Alternative Sequence

283..289; RVYVSGL -> SSLVKRR (in isoform 2); 290..416; Missing (in isoform 2)

Domain & Motif Annotations

Region

1..32; Disordered

Protein Families

Strictosidine synthase family

Sequence Similarities

Belongs to the strictosidine synthase family.

Clinical Relevance4

Antibody (2)

HPA012863 HPA064700

Interaction Protein

ENSG00000127022

Interaction Count

Interaction Dataset

biogrid_opencell

Supporting Publications2

PMID	Title	Abstract
37576973	The proteome and phosphoproteome of circulating extracellular vesicle-enriched preparations are associated with characteristic clinical features in type 1 diabetes.	No abstract available
40222457	Proteome alterations in peripheral immune cells of DLBCL patients and evidence of cancer extracellular vesicles involvement.	No abstract available