Protein detail
C1QR1
Complement component C1q receptor (C1q/MBL/SPA receptor) (C1qR) (C1qR(p)) (C1qRp) (CDw93) (Complement component 1 q subcomponent receptor 1) (Matrix-remodeling-associated protein 4) (CD antigen CD93)
Protein symbol C1QR1 | UniProt ID | EVMP score 0.50 |
Frequency 1 | Transmembrane count 1 | Protein classification CD markersPlasma proteinsPredicted membrane proteins |
Basic Information
Protein Names
Complement component C1q receptor (C1q/MBL/SPA receptor) (C1qR) (C1qR(p)) (C1qRp) (CDw93) (Complement component 1 q subcomponent receptor 1) (Matrix-remodeling-associated protein 4) (CD antigen CD93)
Protein Class
CD markersPlasma proteinsPredicted membrane proteins
Protein Function
CD markers
Transmembrane
581..601; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym
C1qR(P)C1QR1C1qRPCDw93dJ737E23.1ECSM3MXRA4
Gene Description
CD93 molecule
Chromosome
20
Position
23079360-23086324
Frequency
1
EVMP Score
0.50
Fluorescence & Localization
Cell SpecificConjunctival goblet cellsSingle-Nuclei Brain Specificoligodendrocyte
Function & Pathway
Protein Function
CD markers
Cellular Component
Molecular Function
Biological Process
Canonical Pathways
M286 Pid tgfbr pathway
Mediation Categories
Fusion and delivery mediationImmune mediation
Relations & Evidence
Enzyme-Mediated Modification
Ligand-Receptor Signaling
57 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transmembrane | transmembrane | TopDB | No | No | No | Yes | No |
| transmembrane | transmembrane | LOCATE | No | No | No | Yes | No |
| transmembrane | transmembrane | Ramilowski_location | No | No | No | Yes | No |
| transmembrane | transmembrane | OmniPath | No | No | No | Yes | No |
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | Yes | No |
| plasma_membrane | plasma_membrane | Cellinker | No | No | No | Yes | No |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | Yes | No |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | Membranome | No | No | No | Yes | No |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | HPMR | No | No | No | Yes | No |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | OmniPath | No | No | No | Yes | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Mass spectrometryMass spectrometry [LTQ-FT Ultra] | 1 | 40089067 |
Sequence, Structure & Domains
Sequences
Length
652
Mass
68,560
Sequence
MATSMGLLLLLLLLLTQPGAGTGADTEAVVCVGTACYTAHSGKLSAAEAQNHCNQNGGNLATVKSKEEAQHVQRVLAQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGFSWVGGGEDTPYSNWHKELRNSCISKRCVSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVCKFSFKGMCRPLALGGPGQVTYTTPFQTTSSSLEAVPFASAANVACGEGDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGSPGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLLLFYILGTVVAILLLLALALGLLVYRKRRAKREEKKEKKPQNAADSYSWVPERAESRAMENQYSPTPGTDC
3D Structural Models
Turn
110..113; 260..266
Helix
46..55; 66..82; 267..270
Beta Strand
29..32; 35..41; 89..99; 101..103; 136..138; 140..147; 154..156; 159..163; 175..183; 198..202; 204..206; 208..210; 213..216; 220..224; 237..239; 241..244; 247..249; 272..277; 279..281; 283..286; 291..293; 300..302
3D Structure
X-ray crystallography (2)
Domain & Motif Annotations
Compositional Bias
512..526; Polar residues; 612..621; Basic and acidic residues; 640..652; Polar residues
Domain (FT)
32..174; C-type lectin; 260..301; EGF-like 1; 302..344; EGF-like 2; 345..384; EGF-like 3; calcium-binding; 385..426; EGF-like 4; calcium-binding; 427..468; EGF-like 5; calcium-binding
Region
472..546; Disordered; 553..572; Disordered; 611..652; Disordered