Protein detail
TRM13
tRNA:m(4)X modification enzyme TRM13 homolog (EC 2.1.1.225) (Coiled-coil domain-containing protein 76)
Entry name TRM13 | UniProt ID | EVMP confidence score 0.38 |
Supporting publications (n) 1 | Transmembrane count | Protein classification EnzymesPredicted intracellular proteins |
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40Basic Information11
Protein Names
tRNA:m(4)X modification enzyme TRM13 homolog (EC 2.1.1.225) (Coiled-coil domain-containing protein 76)
Protein Class (2)
EnzymesPredicted intracellular proteins
Protein Function (3)
- ENZYME proteins:Transferases
- Enzymes
- Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym (3)
CCDC76FLJ10287FLJ11219
Gene Description
TRNA methyltransferase 13 homolog
Chromosome
1
Position
100133150-100150496
Supporting publications (n)
1
EVMP confidence score
0.38
Function & Pathway5
Protein Function (3)
- ENZYME proteins:Transferases
- Enzymes
- Predicted intracellular proteins
Molecular Function (3)
Biological Process (3)
Reactome (3)
Mediation Categories
Other mediation
Relations & Evidence3
Ligand-Receptor Signaling (2)
2 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationSize Exclusion ChromatographyImmunoaffinity Capture | Western blotting | 1 | 40098346 |
Sequence, Structure & Domains10
Sequences
Length
481
Mass
54,247
Sequence
MATSATSPHAPGFPAEGRCGYYVEKKKRFCRMVVAAGKRFCGEHAGAAEEEDARKRILCPLDPKHTVYEDQLAKHLKKCNSREKPKPDFYIQDINAGLRDETEIPEQLVPISSLSEEQLEKLIKKLRKASEGLNSTLKDHIMSHPALHDALNDPKNGDSATKHLKQQASILGNIENLKLLGPRRCFVEFGAGKGKLSHWVDIALKDAEKVHFILVEKVTTRFKVDGKHRKKNSVFERLQIDIQHLCLNKIPVLREEKLPVVGIGKHLCGMATDLALRCLVETYAASFEERNEEPLAKRIKNDKTEKEIYTLAKEGNEKNVPEKWNPVAGIVIALCCHHRCDWRHYVGKEYFRALGLGAVEFHYFQRMSSWATCGMRKTSLETSNSTTKRQDNQNDDSEEHDDGGYRITDDGADCLPGLLSVEEKKKIGHLCKLLIDQGRIQYLQQKGFSPALQYYTDPLVSLENVLLTALPNHSSSPETTA
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9NUP7-1; Sequence=Displayed; Name=2; IsoId=Q9NUP7-2; Sequence=VSP_018578, VSP_018579
Alternative Sequence
168..175; ASILGNIE -> VCLGYSNY (in isoform 2); 176..481; Missing (in isoform 2)
Domain & Motif Annotations
Coiled Coil
113..140
Zinc Finger
56..83; CHHC U11-48K-type
Region
381..408; Disordered
Protein Families
Methyltransferase TRM13 family
Sequence Similarities
Belongs to the methyltransferase TRM13 family.
Clinical Relevance1
Antibody
Supporting Publications1
| PMID | Title | Abstract |
|---|---|---|
| 36146834 | Human Cytomegalovirus Modifies Placental Small Extracellular Vesicle Composition to Enhance Infection of Fetal Neural Cells In Vitro. | No abstract available |