Protein detail

UQCC1

Ubiquinol-cytochrome c reductase complex assembly factor 1 (Basic FGF-repressed Zic-binding protein) (bFGF-repressed Zic-binding protein) (bFZb) (Ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog)

Entry name UQCC1	UniProt ID Q9NVA1	EVMP score 0.50
Frequency 1	Transmembrane count	Protein classification Plasma proteinsPredicted intracellular proteinsPredicted membrane proteins

EVMP score: annotation confidence score.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information

Protein Names

Protein Class

Plasma proteinsPredicted intracellular proteinsPredicted membrane proteins

Protein Function

Predicted intracellular proteins

Ensembl

ENSG00000101019

Entrez Gene Symbol

UQCC1

Gene Synonym

BFZBC20orf44CBP3FLJ10850UQCC

Gene Description

Ubiquinol-cytochrome c reductase complex assembly factor 1

Chromosome

Position

35302566-35412031

Frequency

EVMP Score

0.50

Fluorescence & Localization

Cell SpecificChoroid plexus epithelial cells

Function & Pathway

Protein Function

Predicted intracellular proteins

Cellular Component

Molecular Function

GO:0005515 protein binding

Reactome

Mediation Categories

Metabolism mediation

Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

7 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
intracellular	intracellular	ComPPI	No	No	No	No	No
intracellular	intracellular	GO_Intercell	No	No	No	No	No
intracellular	intracellular	UniProt_location	No	No	No	No	No
intracellular	intracellular	OmniPath	No	No	No	No	No
transmembrane	transmembrane	Ramilowski_location	No	No	No	No	No
transmembrane	transmembrane	OmniPath	No	No	No	No	No
transmembrane	transmembrane_predicted	Phobius	No	No	No	No	No

Regulatory Interaction Network

0 records.

Protein Complex Composition

2 records.

Component Name	Component Gene Symbols	Component UniProt ID	Stoichiometry	Database	Database IDs	References
	COX20 UQCC1 UQCC2 UQCC4	Q4G0I0 Q5RI15 Q9BRT2 Q9NVA1	0:0:0:0	hu.MAP
	UQCC1 UQCC2	Q9BRT2 Q9NVA1	0:0	hu.MAP2

Isolation & Detection Technology

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential UltracentrifugationSize Exclusion Chromatography	Mass spectrometry	2	35212939 27894104

Sequence, Structure & Domains

Sequences

Length

299

Mass

34,600

Sequence

MALLVRVLRNQTSISQWVPVCSRLIPVSPTQGQGDRALSRTSQWPQMSQSRACGGSEQIPGIDIQLNRKYHTTRKLSTTKDSPQPVEEKVGAFTKIIEAMGFTGPLKYSKWKIKIAALRMYTSCVEKTDFEEFFLRCQMPDTFNSWFLITLLHVWMCLVRMKQEGRSGKYMCRIIVHFMWEDVQQRGRVMGVNPYILKKNMILMTNHFYAAILGYDEGILSDDHGLAAALWRTFFNRKCEDPRHLELLVEYVRKQIQYLDSMNGEDLLLTGEVSWRPLVEKNPQSILKPHSPTYNDEGL

Alternative Products

Event=Alternative splicing; Named isoforms=5; Name=1; IsoId=Q9NVA1-1; Sequence=Displayed; Name=2; IsoId=Q9NVA1-2; Sequence=VSP_000857; Name=3; IsoId=Q9NVA1-3; Sequence=VSP_000855, VSP_000856; Name=4; IsoId=Q9NVA1-4; Sequence=VSP_016027; Name=5; IsoId=Q9NVA1-5; Sequence=VSP_043406

Alternative Sequence

1..112; Missing (in isoform 3); 44..111; Missing (in isoform 5); 109..135; Missing (in isoform 4); 113..136; IKIAALRMYTSCVEKTDFEEFFLR -> MQPIDTCVSYPRTGSVSHFPG (in isoform 3); 192..217; Missing (in isoform 2)

3D Structural Models

Domain & Motif Annotations

Protein Families

CBP3 family

Sequence Similarities

Belongs to the CBP3 family.

Clinical Relevance

Antibody

HPA034875

Interaction Protein

ENSG00000137288

Interaction Count

Interaction Dataset

intact_biogrid_bioplex