Protein detail

S38A7

Sodium-coupled neutral amino acid transporter 7 (Solute carrier family 38 member 7)

Entry name
S38A7
UniProt ID
EVMP score
0.50
Frequency
1
Transmembrane count
11
Protein classification
Predicted membrane proteinsTransporters
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Sodium-coupled neutral amino acid transporter 7 (Solute carrier family 38 member 7)
Protein Class
Predicted membrane proteinsTransporters
Protein Function
Transporters:Electrochemical Potential-driven transporters
Transmembrane
56..76; Helical; 82..102; Helical; 130..150; Helical; 178..198; Helical; 205..225; Helical; 239..259; Helical; 282..302; Helical; 319..339; Helical; 371..391; Helical; 395..415; Helical; 428..448; Helical
Transmembrane Count
11
Entrez Gene Symbol
Gene Synonym
FLJ10815
Gene Description
Solute carrier family 38 member 7
Chromosome
16
Position
58665109-58684770
Frequency
1
EVMP Score
0.50
Fluorescence & Localization
Tissue Specificbone marrowCell SpecificMegakaryocyte progenitorsSingle-Nuclei Brain Specificcentral nervous system macrophageBlood Cell Specificeosinophil
Function & Pathway
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

14 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
transmembranetransmembraneRamilowski_locationNoNoNoNoNo
transmembranetransmembraneOmniPathNoNoNoNoNo
receptorreceptorscConnectNoYesNoNoNo
transmembranetransmembrane_predictedPhobiusNoNoNoNoNo
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Regulatory Interaction Network

0 records.

Protein Complex Composition

0 records.

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyMass spectrometry3352129394074865833709510
Sequence, Structure & Domains

Sequences

Length
462
Mass
49,966
Sequence
MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVWAVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTISLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPASWMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYQGVPVEEDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFVFPGLCLIQAKLSEMEEVKPASWWVLVSYGVLLVTLGAFIFGQTTANAIFVDLLA
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9NVC3-1; Sequence=Displayed; Name=2; IsoId=Q9NVC3-2; Sequence=VSP_031511
Alternative Sequence
345..462; Missing (in isoform 2)

3D Structural Models

Domain & Motif Annotations

Protein Families
Amino acid/polyamine transporter 2 family
Sequence Similarities
Belongs to the amino acid/polyamine transporter 2 family.
Clinical Relevance