Protein detail

FAIM1

Fas apoptotic inhibitory molecule 1

Entry name
FAIM1
UniProt ID
Q9NVQ4
EVMP confidence score
0.53
Supporting publications (n)
2
Transmembrane count
Protein classification
Predicted intracellular proteins
Basic Information
Protein Names
Fas apoptotic inhibitory molecule 1
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
ENSG00000158234
Entrez Gene Symbol
FAIM
Gene Synonym (2)
FAIM1FLJ10582
Gene Description
Fas apoptotic inhibitory molecule
Chromosome
3
Position
138608606-138633376
Supporting publications (n)
2
EVMP confidence score
0.53
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
GO:0005737 cytoplasm
Molecular Function
GO:0005515 protein binding
Mediation Categories
Receptor-signaling mediation
Relations & Evidence5

Ligand-Receptor Signaling (4)

4 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPI
intracellularintracellularGO_Intercell
intracellularintracellularUniProt_location
intracellularintracellularOmniPath

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationWestern blotting24130796833905554
Sequence, Structure & Domains

Sequences

Length
179
Mass
20,215
Sequence
MTDLVAVWDVALSDGVHKIEFEHGTTSGKRVVYVDGKEEIRKEWMFKLVGKETFYVGAAKTKATINIDAISGFAYEYTLEINGKSLKKYMEDRSKTTNTWVLHMDGENFRIVLEKDAMDVWCNGKKLETAGEFVDDGTETHFSIGNHDCYIKAVSSGKRKEGIIHTLIVDNREIPEIAS
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; Synonyms=FAIM-S; IsoId=Q9NVQ4-1; Sequence=Displayed; Name=2; IsoId=Q9NVQ4-2; Sequence=VSP_008991; Name=3; Synonyms=FAIM-L; IsoId=Q9NVQ4-3; Sequence=VSP_038095
Alternative Sequence
1; M -> MLLPFIRTLPLLCYNHLLVSPDSATLSPPYSLEKM (in isoform 2); 1; M -> MASGDDSPIFEDDESPPYSLEKM (in isoform 3)

3D Structural Models

Turn
25..27; 57..60; 71..73; 115..118
Beta Strand
4..12; 15..23; 30..34; 37..42; 50..56; 61..70; 74..81; 84..88; 98..104; 107..114; 119..122; 125..127; 130..134; 137..144; 147..154; 157..160; 164..169; 172..174
3D Structure
NMR spectroscopy (1); X-ray crystallography (1)

Domain & Motif Annotations

Protein Families
FAIM1 family
Sequence Similarities
Belongs to the FAIM1 family.
Clinical Relevance
Antibody (2)
HPA042440HPA052209
Supporting Publications2
PMIDTitleRelated sentences
38731868The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer.No related sentences available
40098346Toward Identification of Markers for Brain-Derived Extracellular Vesicles in Cerebrospinal Fluid: A Large-Scale, Unbiased Analysis Using Proximity Extension Assays.No related sentences available