Protein detail
FAIM1
Fas apoptotic inhibitory molecule 1
Entry name FAIM1 | UniProt ID | EVMP confidence score 0.38 |
Supporting publications (n) 2 | Transmembrane count | Protein classification Predicted intracellular proteins |
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40Basic Information11
Protein Names
Fas apoptotic inhibitory molecule 1
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym (2)
FAIM1FLJ10582
Gene Description
Fas apoptotic inhibitory molecule
Chromosome
3
Position
138608606-138633376
Supporting publications (n)
2
EVMP confidence score
0.38
Function & Pathway4
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Mediation Categories
Receptor-signaling mediation
Relations & Evidence5
Ligand-Receptor Signaling (4)
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Sequence, Structure & Domains10
Sequences
Length
179
Mass
20,215
Sequence
MTDLVAVWDVALSDGVHKIEFEHGTTSGKRVVYVDGKEEIRKEWMFKLVGKETFYVGAAKTKATINIDAISGFAYEYTLEINGKSLKKYMEDRSKTTNTWVLHMDGENFRIVLEKDAMDVWCNGKKLETAGEFVDDGTETHFSIGNHDCYIKAVSSGKRKEGIIHTLIVDNREIPEIAS
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; Synonyms=FAIM-S; IsoId=Q9NVQ4-1; Sequence=Displayed; Name=2; IsoId=Q9NVQ4-2; Sequence=VSP_008991; Name=3; Synonyms=FAIM-L; IsoId=Q9NVQ4-3; Sequence=VSP_038095
Alternative Sequence
1; M -> MLLPFIRTLPLLCYNHLLVSPDSATLSPPYSLEKM (in isoform 2); 1; M -> MASGDDSPIFEDDESPPYSLEKM (in isoform 3)
3D Structural Models
Turn
25..27; 57..60; 71..73; 115..118
Beta Strand
4..12; 15..23; 30..34; 37..42; 50..56; 61..70; 74..81; 84..88; 98..104; 107..114; 119..122; 125..127; 130..134; 137..144; 147..154; 157..160; 164..169; 172..174
3D Structure
NMR spectroscopy (1); X-ray crystallography (1)
Domain & Motif Annotations
Protein Families
FAIM1 family
Sequence Similarities
Belongs to the FAIM1 family.
Supporting Publications2
| PMID | Title | Abstract |
|---|---|---|
| 38731868 | The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer. | No abstract available |
| 40098346 | Toward Identification of Markers for Brain-Derived Extracellular Vesicles in Cerebrospinal Fluid: A Large-Scale, Unbiased Analysis Using Proximity Extension Assays. | No abstract available |