Protein detail

FAIM1

Fas apoptotic inhibitory molecule 1

Entry name
FAIM1
UniProt ID
EVMP score
0.38
Frequency
2
Transmembrane count
Protein classification
Predicted intracellular proteins
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Fas apoptotic inhibitory molecule 1
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Entrez Gene Symbol
Gene Synonym
FAIM1FLJ10582
Gene Description
Fas apoptotic inhibitory molecule
Chromosome
3
Position
138608606-138633376
Frequency
2
EVMP Score
0.38
Fluorescence & Localization
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Mediation Categories
Receptor-signaling mediation
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

4 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularGO_IntercellNoNoNoNoNo
intracellularintracellularUniProt_locationNoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo

Regulatory Interaction Network

0 records.

Protein Complex Composition

0 records.

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationWestern blotting24130796833905554
Sequence, Structure & Domains

Sequences

Length
179
Mass
20,215
Sequence
MTDLVAVWDVALSDGVHKIEFEHGTTSGKRVVYVDGKEEIRKEWMFKLVGKETFYVGAAKTKATINIDAISGFAYEYTLEINGKSLKKYMEDRSKTTNTWVLHMDGENFRIVLEKDAMDVWCNGKKLETAGEFVDDGTETHFSIGNHDCYIKAVSSGKRKEGIIHTLIVDNREIPEIAS
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; Synonyms=FAIM-S; IsoId=Q9NVQ4-1; Sequence=Displayed; Name=2; IsoId=Q9NVQ4-2; Sequence=VSP_008991; Name=3; Synonyms=FAIM-L; IsoId=Q9NVQ4-3; Sequence=VSP_038095
Alternative Sequence
1; M -> MLLPFIRTLPLLCYNHLLVSPDSATLSPPYSLEKM (in isoform 2); 1; M -> MASGDDSPIFEDDESPPYSLEKM (in isoform 3)

3D Structural Models

Turn
25..27; 57..60; 71..73; 115..118
Beta Strand
4..12; 15..23; 30..34; 37..42; 50..56; 61..70; 74..81; 84..88; 98..104; 107..114; 119..122; 125..127; 130..134; 137..144; 147..154; 157..160; 164..169; 172..174
3D Structure
NMR spectroscopy (1); X-ray crystallography (1)

Domain & Motif Annotations

Protein Families
FAIM1 family
Sequence Similarities
Belongs to the FAIM1 family.
Clinical Relevance