Protein detail
M4A12
Membrane-spanning 4-domains subfamily A member 12
Protein symbol M4A12 | UniProt ID | EVMP score 0.50 |
Frequency 2 | Transmembrane count 4 | Protein classification Predicted membrane proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Membrane-spanning 4-domains subfamily A member 12
Protein Class
Predicted membrane proteins
Transmembrane
92..112; Helical; 121..141; Helical; 161..181; Helical; 201..221; Helical
Transmembrane Count
4
Ensembl
Entrez Gene Symbol
Gene Synonym
FLJ20217Ms4a10
Gene Description
Membrane spanning 4-domains A12
Chromosome
11
Position
60492778-60507430
Frequency
2
EVMP Score
0.50
Fluorescence & Localization
Function & Pathway
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
6 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transmembrane | transmembrane | UniProt_location | No | No | No | No | No |
| transmembrane | transmembrane | UniProt_topology | No | No | No | No | No |
| transmembrane | transmembrane | UniProt_keyword | No | No | No | No | No |
| transmembrane | transmembrane | Ramilowski_location | No | No | No | No | No |
| transmembrane | transmembrane | OmniPath | No | No | No | No | No |
| transmembrane | transmembrane_predicted | Phobius | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Mass spectrometryMass spectrometry [LTQ-FT Ultra]Small R sequencing (Illumi HiSeq 2000 (Solexa) | 1 | 37633233 |
Sequence, Structure & Domains
Sequences
Length
267
Mass
28,069
Sequence
MMSSKPTSHAEVNETIPNPYPPSSFMAPGFQQPLGSINLENQAQGAQRAQPYGITSPGIFASSQPGQGNIQMINPSVGTAVMNFKEEAKALGVIQIMVGLMHIGFGIVLCLISFSFREVLGFASTAVIGGYPFWGGLSFIISGSLSVSASKELSRCLVKGSLGMNIVSSILAFIGVILLLVDMCINGVAGQDYWAVLSGKGISATLMIFSLLEFFVACATAHFANQANTTTNMSVLVIPNMYESNPVTPASSSAPPRCNNYSANAPK
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9NXJ0-1; Sequence=Displayed; Name=2; IsoId=Q9NXJ0-2; Sequence=VSP_044899
Alternative Sequence
93..138; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Region
248..267; Disordered
Protein Families
MS4A family
Sequence Similarities
Belongs to the MS4A family.