Protein detail

SNTG2

Gamma-2-syntrophin (G2SYN) (Syntrophin-5) (SYN5)

Entry name
SNTG2
UniProt ID
EVMP score
0.50
Frequency
1
Transmembrane count
Protein classification
Predicted intracellular proteins
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Gamma-2-syntrophin (G2SYN) (Syntrophin-5) (SYN5)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Entrez Gene Symbol
Gene Synonym
G2SYNSYN5
Gene Description
Syntrophin gamma 2
Chromosome
2
Position
950849-1367613
Frequency
1
EVMP Score
0.50
Fluorescence & Localization
SNTG2 fluorescence
Cell SpecificColonocytesSingle-Nuclei Brain SpecificpericyteBlood Cell Specificnon-classical monocyteBlood Lineage Specificmonocytes
Function & Pathway
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

7 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularLOCATENoNoNoNoNo
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularGO_IntercellNoNoNoNoNo
intracellularintracellularUniProt_locationNoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo
plasma_membraneplasma_membraneUniProt_locationNoNoNoNoNo
plasma_membraneplasma_membraneOmniPathNoNoNoNoNo

Regulatory Interaction Network

0 records.

Protein Complex Composition

1 record.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
syntrophin complexSNTG1SNTG2Q9NSN8Q9NY991:1CompleatCompleat:HC235410747910

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Mass spectrometry0
Sequence, Structure & Domains

Sequences

Length
539
Mass
60,217
Sequence
MGTEGPPPPAASRGRQGCLLVPARTKTTIALLYDEESENAYDIRLKLTKEVLTIQKQDVVCVGGSHQGRNRRTVTLRRQPVGGLGLSIKGGSEHNVPVVISKIFEDQAADQTGMLFVGDAVLQVNGIHVENATHEEVVHLLRNAGDEVTITVEYLREAPAFLKLPLGSPGPSSDHSSGASSPLFDSGLHLNGNSSTTAPSSPSSPIAKDPRYEKRWLDTLSVPLSMARISRYKAGTEKLRWNAFEVLALDGVSSGILRFYTAQDGTDWLRAVSANIRELTLQNMKMANKCCSPSDQVVHMGWVNEKLQGADSSQTFRPKFLALKGPSFYVFSTPPVSTFDWVRAERTYHLCEVLFKVHKFWLTEDCWLQANLYLGLQDFDFEDQRPYCFSIVAGHGKSHVFNVELGSELAMWEKSFQRATFMEVQRTGSRTYMCSWQGEMLCFTVDFALGFTCFESKTKNVLWRFKFSQLKGSSDDGKTRVKLLFQNLDTKQIETKELEFQDLRAVLHCIHSFIAAKVASVDPGFMDSQSLARKYMYSS
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9NY99-1; Sequence=Displayed; Name=2; IsoId=Q9NY99-2; Sequence=VSP_039175
Alternative Sequence
71..197; Missing (in isoform 2)

3D Structural Models

Turn
80..82
Helix
92..94; 108..112; 134..142
Beta Strand
72..77; 86..91; 96..103; 120..124; 146..153
3D Structure
X-ray crystallography (1)

Domain & Motif Annotations

Compositional Bias
168..183; Low complexity; 194..205; Low complexity
Domain (CC)
The association with dystrophin or related proteins probably leaves the PDZ domain available to recruit proteins to the membrane.
Domain (FT)
73..156; PDZ; 296..421; PH
Region
168..209; Disordered
Protein Families
Syntrophin family
Sequence Similarities
Belongs to the syntrophin family.
Clinical Relevance
Interaction Protein
ENSG00000138101
Interaction Count
1
Interaction Dataset
intact_biogrid