Protein detail
GTSE1
G2 and S phase-expressed protein 1 (GTSE-1) (Protein B99 homolog)
Protein symbol GTSE1 | UniProt ID | EVMP score 0.38 |
Frequency 1 | Transmembrane count | Protein classification |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
G2 and S phase-expressed protein 1 (GTSE-1) (Protein B99 homolog)
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Reactome
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
4 records.
| Substrate Gene Symbol | Enzyme Gene Symbol | Enzyme UniProt ID | Residue Type | Residue Offset | Modification | Database | References |
|---|---|---|---|---|---|---|---|
| GTSE1 | PLK1 | P53350 | S | 435 | phosphorylation | Sparser_ProtMapperSIGNORProtMapperRLIMS-P_ProtMapperSIGNOR_ProtMapperREACH_ProtMapperPhosphoSitePhosphoSite_ProtMapper | ProtMapper:27330107ProtMapper:23948487ProtMapper:22852086ProtMapper:20577264SIGNOR:20577264ProtMapper:28415805 |
| GTSE1 | PLK1 | P53350 | S | 223 | phosphorylation | PhosphoSitePhosphoSite_ProtMapperProtMapper | |
| GTSE1 | CSNK1E | P49674 | S | 592 | phosphorylation | KEA | KEA:17570479 |
| GTSE1 | GSK3B | P49841 | S | 592 | phosphorylation | KEA | KEA:17570479 |
Ligand-Receptor Signaling
5 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | LOCATE | No | No | No | No | No |
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
1 record.
| Source Protein Symbol | Source UniProt ID | Target Protein Symbol | Target UniProt ID | Is Directed | Is Stimulation | Is Inhibition | Database | References |
|---|---|---|---|---|---|---|---|---|
| PLK1 | P53350 | GTSE1 | Q9NYZ3 | Yes | Yes | No | Sparser_ProtMapperPhosphoSite_MIMPMIMPHPRD_MIMPPhosphoSite_norefSIGNORiPTMnetProtMapperRLIMS-P_ProtMapperSIGNOR_ProtMapperREACH_ProtMapperPhosphoSitePhosphoSite_ProtMapper | ProtMapper:27330107ProtMapper:23948487ProtMapper:22852086ProtMapper:20577264SIGNOR:20577264ProtMapper:28415805PhosphoSite:20577264ProtMapper:30862113 |
Protein Complex Composition
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation；Acoustic trapping | Mass spectrometry | 1 | 27487081 |
Sequence, Structure & Domains
Sequences
Length
739
Mass
78,505
Sequence
MEGGGGRDEPSACRAGDVNMDDPKKEDILLLADEKFDFDLSLSSSSANEDDEVFFGPFGHKERCIAASLELNNPVPEQPPLPTSESPFAWSPLAGEKFVEVYKEAHLLALHIESSSRNQAAQAAKPEDPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPLLGPPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSAWRVSALPTPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRVPQALNFSPEESDSTFSKSTATEVAREEAKPGGDAAPSEALLVDIKLEPLAVTPDAASQPLIDLPLIDFCDTPEAHVAVGSESRPLIDLMTNTPDMNKNVAKPSPVVGQLIDLSSPLIQLSPEADKENVDSPLLKF
3D Structural Models
3D Structure
X-ray crystallography (2)
Domain & Motif Annotations
Compositional Bias
1..11; Basic and acidic residues; 149..165; Basic and acidic residues; 181..195; Low complexity; 268..280; Basic and acidic residues; 284..294; Low complexity; 330..342; Low complexity; 360..372; Polar residues; 411..424; Low complexity; 430..446; Polar residues; 455..470; Polar residues; 481..522; Polar residues; 577..590; Basic and acidic residues
Region
1..20; Disordered; 116..136; Disordered; 149..306; Disordered; 320..639; Disordered
Clinical Relevance
Interaction Protein
ENSG00000101367ENSG00000122705
Interaction Count
2
Interaction Dataset
biogrid_opencell