Protein detail
ARP10
Actin-related protein 10 (Actin-related protein 11) (hARP11)
Entry name ARP10 | UniProt ID | EVMP confidence score 0.38 |
Supporting publications (n) 1 | Transmembrane count | Protein classification |
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40Basic Information6
Protein Names
Actin-related protein 10 (Actin-related protein 11) (hARP11)
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Supporting publications (n)
1
EVMP confidence score
0.38
Function & Pathway7
Protein Function
Predicted intracellular proteins
Cellular Component (7)
Molecular Function
Biological Process (3)
KEGG (5)
Reactome (16)
- R-hsa-1280218 adaptive immune system
- R-hsa-446203 asparagine n linked glycosylation
- R-hsa-8953897 cellular responses to stimuli
- R-hsa-6811436 copi independent golgi to er retrograde traffic
- R-hsa-6807878 copi mediated anterograde transport
- R-hsa-199977 er to golgi anterograde transport
- R-hsa-8856688 golgi to er retrograde transport
- R-hsa-3371497 hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand
- R-hsa-168249 innate immune system
- R-hsa-6811442 intra golgi and retrograde golgi to er traffic
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Mediation Categories (3)
Fusion and delivery mediationImmune mediationMetabolism mediation
Relations & Evidence7
Ligand-Receptor Signaling (6)
6 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| ecm | ecm | MatrixDB | Yes | No | No | No | No |
| ecm | ecm | OmniPath | Yes | No | No | No | No |
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Mass spectrometry | 1 | 27863537 |
Sequence, Structure & Domains6
Sequences
Length
417
Mass
46,307
Sequence
MPLYEGLGSGGEKTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKRAGMPKPVRVVQYNINTEELYSYLKEFIHILYFRHLLVNPRDRRVVIIESVLCPSHFRETLTRVLFKYFEVPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPVLNCWGALPLGGKALHKELETQLLEQCTVDTSVAKEQSLPSVMGSVPEGVLEDIKARTCFVSDLKRGLKIQAAKFNIDGNNERPSPPPNVDYPLDGEKILHILGSIRDSVVEILFEQDNEEQSVATLILDSLIQCPIDTRKQLAENLVVIGGTSMLPGFLHRLLAEIRYLVEKPKYKKALGTKTFRIHTPPAKANCVAWLGGAIFGALQDILGSRSVSKEYYNQTGRIPDWCSLNNPPLEMMFDVGKTQPPLMKRAFSTEK
3D Structural Models
3D Structure
Electron microscopy (2)
Domain & Motif Annotations
Protein Families
Actin family
Sequence Similarities
Belongs to the actin family.
Clinical Relevance3
Interaction Protein (7)
ENSG00000077380ENSG00000077549ENSG00000115073ENSG00000132912ENSG00000138107ENSG00000175203ENSG00000204843
Interaction Count
7
Interaction Dataset (4)
biogrid_opencellbiogrid_bioplexintact_biogridintact_biogrid_opencell
Supporting Publications1
| PMID | Title | Abstract |
|---|---|---|
| 34771645 | GCC2 as a New Early Diagnostic Biomarker for Non-Small Cell Lung Cancer. | No abstract available |