Protein detail
CALL5
Calmodulin-like protein 5 (Calmodulin-like skin protein)
Entry name CALL5 | UniProt ID | EVMP confidence score 0.53 |
Supporting publications (n) 4 | Transmembrane count | Protein classification Plasma proteinsPredicted intracellular proteinsRAS pathway related proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Calmodulin-like protein 5 (Calmodulin-like skin protein)
Protein Class (3)
Plasma proteinsPredicted intracellular proteinsRAS pathway related proteins
Protein Function (2)
- Predicted intracellular proteins
- RAS pathway related proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
CLSP
Gene Description
Calmodulin like 5
Chromosome
10
Position
5498697-5499570
Supporting publications (n)
4
EVMP confidence score
0.53
Fluorescence & Localization
Tissue Specificsalivary glandCell SpecificAdrenal medulla cellsSingle-Nuclei Brain SpecificpericyteBlood Cell SpecificbasophilBlood Lineage Specificdendritic cells
Function & Pathway
Protein Function (2)
- Predicted intracellular proteins
- RAS pathway related proteins
Cellular Component (3)
Molecular Function (3)
Biological Process (3)
KEGG (43)
- hsa04014 Ras signaling pathway
- KEGG:hsa04015 Rap1 signaling pathway
- KEGG:hsa04020 Calcium signaling pathway
- KEGG:hsa04022 cGMP-PKG signaling pathway
- KEGG:hsa04024 cAMP signaling pathway
- KEGG:hsa04070 Phosphatidylinositol signaling system
- KEGG:hsa04114 Oocyte meiosis
- KEGG:hsa04218 Cellular senescence
- KEGG:hsa04261 Adrenergic signaling in cardiomyocytes
- KEGG:hsa04270 Vascular smooth muscle contraction
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Reactome (5)
Mediation Categories
Immune mediation
Relations & Evidence8
Ligand-Receptor Signaling (5)
5 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| ecm | ecm | MatrixDB | Yes | ||||
| ecm | ecm | OmniPath | Yes | ||||
| intracellular | intracellular | ComPPI | |||||
| intracellular | intracellular | GO_Intercell | |||||
| intracellular | intracellular | OmniPath |
Protein Complex Composition (2)
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion Chromatography | Flow cytometry | 1 | 35611462 |
Sequence, Structure & Domains
Sequences
Length
146
Mass
15,893
Sequence
MAGELTPEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDGDGEISFQEFLTAAKKARAGLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFARMLAQE
3D Structural Models
Helix
80..87; 100..106; 107..109; 116..125; 138..143
Beta Strand
93..99; 128..135
3D Structure
NMR spectroscopy (1)
Domain & Motif Annotations
Domain (FT)
8..43; EF-hand 1; 44..74; EF-hand 2; 78..113; EF-hand 3; 114..146; EF-hand 4
Clinical Relevance
Antibody
Interaction Protein
ENSG00000158828
Interaction Count
1
Interaction Dataset
biogrid_bioplex
Supporting Publications4
| PMID | Title | Related sentences |
|---|---|---|
| 26775013 | Proteomic characterization of circulating extracellular vesicles identifies novel serum myeloma associated markers. | No related sentences available |
| 30071318 | Changes in the urinary extracellular vesicle proteome are associated with nephronophthisis-related ciliopathies. | No related sentences available |
| 36362114 | Extracellular Vesicles in Diffuse Large B Cell Lymphoma: Characterization and Diagnostic Potential. | No related sentences available |
| 38731868 | The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer. | No related sentences available |