Protein detail

RAB26

Ras-related protein Rab-26 (EC 3.6.5.2)

Entry name
RAB26
UniProt ID
Q9ULW5
EVMP confidence score
0.40
Supporting publications (n)
2
Transmembrane count
Protein classification
Basic Information
Protein Names
Ras-related protein Rab-26 (EC 3.6.5.2)
Protein Function
Predicted intracellular proteins
Ensembl
ENSG00000167964
Entrez Gene Symbol
RAB26
Supporting publications (n)
2
EVMP confidence score
0.40
Fluorescence & Localization
RAB26 fluorescence
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component (6)
Molecular Function (4)
Reactome (2)
Mediation Categories (2)
Fusion and delivery mediationMetabolism mediation
Relations & Evidence5

Ligand-Receptor Signaling (4)

4 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPI
intracellularintracellularGO_Intercell
intracellularintracellularUniProt_location
intracellularintracellularOmniPath

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Mass spectrometry0
Sequence, Structure & Domains

Sequences

Length
256
Mass
27,900
Sequence
MSRKKTPKSKGASTPAASTLPTANGARPARSGTALSGPDAPPNGPLQPGRPSLGGGVDFYDVAFKVMLVGDSGVGKTCLLVRFKDGAFLAGTFISTVGIDFRNKVLDVDGVKVKLQMWDTAGQERFRSVTHAYYRDAHALLLLYDVTNKASFDNIQAWLTEIHEYAQHDVALMLLGNKVDSAHERVVKREDGEKLAKEYGLPFMETSAKTGLNVDLAFTAIAKELKQRSMKAPSEPRFRLHDYVKREGRGASCCRP
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9ULW5-1; Sequence=Displayed; Name=2; IsoId=Q9ULW5-2; Sequence=VSP_056879
Alternative Sequence
1..66; Missing (in isoform 2)

3D Structural Models

Turn
208..210
Helix
76..85; 134..136; 149..153; 155..165; 189..198; 214..226
Beta Strand
61..69; 100..108; 111..119; 138..145; 171..177; 203..205
3D Structure
X-ray crystallography (1)

Domain & Motif Annotations

Compositional Bias
12..23; Low complexity
Motif
86..101; Switch 1; 119..136; Switch 2
Domain (CC)
Switch 1, switch 2 and the interswitch regions are characteristic of Rab GTPases and mediate the interactions with Rab downstream effectors. The switch regions undergo conformational changes upon nucleotide binding which drive interaction with specific sets of effector proteins, with most effectors only binding to GTP-bound Rab.
Region
1..51; Disordered
Protein Families (2)
  • Small GTPase superfamily
  • Rab family
Sequence Similarities
Belongs to the small GTPase superfamily. Rab family.
Supporting Publications2
PMIDTitleRelated sentences
38731868The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer.No related sentences available
39835386Comparison of nanoLC-MALDI-MS/MS with nanoLC-TIMS-MS/MS in the proteomic analysis of extracellular vesicles of bronchoalveolar lavage fluid.No related sentences available