Protein detail
COR2B
Coronin-2B (Coronin-like protein C) (Clipin-C) (Protein FC96)
Entry name COR2B | UniProt ID | EVMP confidence score 0.53 |
Supporting publications (n) 2 | Transmembrane count | Protein classification Plasma proteinsPredicted intracellular proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Coronin-2B (Coronin-like protein C) (Clipin-C) (Protein FC96)
Protein Class (2)
Plasma proteinsPredicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym (2)
ClipinCKIAA0925
Gene Description
Coronin 2B
Chromosome
15
Position
68578993-68727806
Supporting publications (n)
2
EVMP confidence score
0.53
Fluorescence & Localization
Tissue SpecificbrainCell SpecificAstrocytesSingle-Nuclei Brain Specificoligodendrocyte
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component (4)
Molecular Function (5)
Biological Process (3)
Canonical Pathways
M206 Pid pdgfra pathway
Mediation Categories (2)
Adhesion and uptake mediationFusion and delivery mediation
Relations & Evidence5
Ligand-Receptor Signaling (4)
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | |||||
| intracellular | intracellular | GO_Intercell | |||||
| intracellular | intracellular | UniProt_location | |||||
| intracellular | intracellular | OmniPath |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationSize Exclusion Chromatography | Mass spectrometry | 20 | 3119696833718342346223203929045939949490409280273150850038225453398737263873186826801919268848413370951036362114246577933849095830760538403116164009145531320591 |
Sequence, Structure & Domains
Sequences
Length
480
Mass
54,953
Sequence
MTVTKMSWRPQYRSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNTRFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPEGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDVGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSDSYQEDIYPMTPGTEPALTPDEWLGGINRDPVLMSLKEGYKKSSKMVFKAPIKEKKSVVVNGIDLLENVPPRTENELLRMFFRQQDEIRRLKEELAQKDIRIRQLQLELKNLRNSPKNC
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9UQ03-1; Sequence=Displayed; Name=2; IsoId=Q9UQ03-2; Sequence=VSP_037706
Alternative Sequence
1..6; MTVTKM -> M (in isoform 2)
Domain & Motif Annotations
Repeat
29..77; WD 1; 78..127; WD 2; 128..170; WD 3; 171..212; WD 4; 213..259; WD 5; 260..305; WD 6; 306..345; WD 7
Coiled Coil
436..479
Protein Families
WD repeat coronin family
Sequence Similarities
Belongs to the WD repeat coronin family.
Clinical Relevance
Antibody
Supporting Publications2
| PMID | Title | Related sentences |
|---|---|---|
| 38395386 | Human gestational diabetes mellitus-derived exosomes impair glucose homeostasis in pregnant mice and stimulate functional maturation of offspring-islets. | No related sentences available |
| 38589887 | The protein composition of exosomes released by prostate cancer cells is distinctly regulated by androgen receptor-antagonists and -agonist to stimulate growth of target cells. | AR ligands augment hub factors in exosomes that include AKT1, CALM1, PAK2 and CTNND1. |