Protein detail
RASD1
Dexamethasone-induced Ras-related protein 1 (Activator of G-protein signaling 1)
Entry name RASD1 | UniProt ID | EVMP confidence score 0.38 |
Supporting publications (n) 1 | Transmembrane count | Protein classification Human disease related genesPredicted intracellular proteins |
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40Basic Information11
Protein Names
Dexamethasone-induced Ras-related protein 1 (Activator of G-protein signaling 1)
Protein Class (2)
Human disease related genesPredicted intracellular proteins
Protein Function (3)
- Human disease related genes:Endocrine and metabolic diseases:Hypothalamus and pituitary gland diseases
- Predicted intracellular proteins
- Human disease related genes:Endocrine and metabolic diseases:Adrenal gland diseases
Ensembl
Entrez Gene Symbol
Gene Synonym (2)
AGS1DEXRAS1
Gene Description
Ras related dexamethasone induced 1
Chromosome
17
Position
17494437-17496395
Supporting publications (n)
1
EVMP confidence score
0.38
Fluorescence & Localization3
Tissue SpecificbrainCell SpecificAstrocytes
Function & Pathway6
Protein Function (3)
- Human disease related genes:Endocrine and metabolic diseases:Hypothalamus and pituitary gland diseases
- Predicted intracellular proteins
- Human disease related genes:Endocrine and metabolic diseases:Adrenal gland diseases
Cellular Component (5)
Molecular Function (4)
Biological Process (3)
Mediation Categories
Receptor-signaling mediation
Relations & Evidence7
Ligand-Receptor Signaling (6)
6 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | No | No |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | No | No |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Mass spectrometry | 0 |
Sequence, Structure & Domains8
Sequences
Length
281
Mass
31,642
Sequence
MKLAAMIKKMCPSDSELSIPAKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFYSIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLRQQILDTKSCLKNKTKENVDVPLVICGNKGDRDFYREVDQREIEQLVGDDPQRCAYFEISAKKNSSLDQMFRALFAMAKLPSEMSPDLHRKVSVQYCDVLHKKALRNKKLLRAGSGGGGGDPGDAFGIVAPFARRPSVHSDLMYIREKASAGSQAKDKERCVIS
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9Y272-1; Sequence=Displayed; Name=2; IsoId=Q9Y272-2; Sequence=VSP_046431, VSP_046432
Alternative Sequence
96..122; GDVFILVFSLDNRDSFEEVQRLRQQIL -> DPRHQVLPQEQNQGERGRAPGHLRQQG (in isoform 2); 123..281; Missing (in isoform 2)
Domain & Motif Annotations
Motif
53..61; Effector region
Protein Families (2)
- Small GTPase superfamily
- RasD family
Sequence Similarities
Belongs to the small GTPase superfamily. RasD family.
Clinical Relevance1
Antibody
Supporting Publications1
| PMID | Title | Abstract |
|---|---|---|
| 34771645 | GCC2 as a New Early Diagnostic Biomarker for Non-Small Cell Lung Cancer. | No abstract available |