Protein detail
RASD1
Dexamethasone-induced Ras-related protein 1 (Activator of G-protein signaling 1)
Protein symbol RASD1 | UniProt ID | EVMP score 0.38 |
Frequency 1 | Transmembrane count | Protein classification Human disease related genesPredicted intracellular proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Dexamethasone-induced Ras-related protein 1 (Activator of G-protein signaling 1)
Protein Class
Human disease related genesPredicted intracellular proteins
Protein Function
- Human disease related genes:Endocrine and metabolic diseases:Hypothalamus and pituitary gland diseases
- Predicted intracellular proteins
- Human disease related genes:Endocrine and metabolic diseases:Adrenal gland diseases
Ensembl
Entrez Gene Symbol
Gene Synonym
AGS1DEXRAS1
Gene Description
Ras related dexamethasone induced 1
Chromosome
17
Position
17494437-17496395
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Tissue SpecificbrainCell SpecificAstrocytes
Function & Pathway
Protein Function
- Human disease related genes:Endocrine and metabolic diseases:Hypothalamus and pituitary gland diseases
- Predicted intracellular proteins
- Human disease related genes:Endocrine and metabolic diseases:Adrenal gland diseases
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Receptor-signaling mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
6 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | No | No |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Mass spectrometry | 0 |
Sequence, Structure & Domains
Sequences
Length
281
Mass
31,642
Sequence
MKLAAMIKKMCPSDSELSIPAKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFYSIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLRQQILDTKSCLKNKTKENVDVPLVICGNKGDRDFYREVDQREIEQLVGDDPQRCAYFEISAKKNSSLDQMFRALFAMAKLPSEMSPDLHRKVSVQYCDVLHKKALRNKKLLRAGSGGGGGDPGDAFGIVAPFARRPSVHSDLMYIREKASAGSQAKDKERCVIS
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9Y272-1; Sequence=Displayed; Name=2; IsoId=Q9Y272-2; Sequence=VSP_046431, VSP_046432
Alternative Sequence
96..122; GDVFILVFSLDNRDSFEEVQRLRQQIL -> DPRHQVLPQEQNQGERGRAPGHLRQQG (in isoform 2); 123..281; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Motif
53..61; Effector region
Protein Families
- Small GTPase superfamily
- RasD family
Sequence Similarities
Belongs to the small GTPase superfamily. RasD family.
Clinical Relevance
Antibody