Protein detail
VWA7
von Willebrand factor A domain-containing protein 7 (Protein G7c)
Entry name VWA7 | UniProt ID | EVMP confidence score 0.28 |
Supporting publications (n) 1 | Transmembrane count | Protein classification Predicted secreted proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
von Willebrand factor A domain-containing protein 7 (Protein G7c)
Protein Class
Predicted secreted proteins
Protein Function
Predicted secreted proteins
Ensembl
Entrez Gene Symbol
Gene Synonym (3)
C6orf27G7cNG37
Gene Description
Von Willebrand factor A domain containing 7
Chromosome
6
Position
31765590-31777328
Supporting publications (n)
1
EVMP confidence score
0.28
Fluorescence & Localization
Cell SpecificCone photoreceptor cells
Function & Pathway
Protein Function
Predicted secreted proteins
Cellular Component (2)
Molecular Function
Biological Process (3)
Canonical Pathways
M267 Pid anthrax pathway
Mediation Categories
Other mediation
Relations & Evidence10
Ligand-Receptor Signaling (9)
9 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| ecm | ecm | MatrixDB | Yes | Yes | |||
| ecm | ecm | OmniPath | Yes | Yes | |||
| intracellular | intracellular | ComPPI | Yes | ||||
| intracellular | intracellular | OmniPath | Yes | ||||
| secreted | secreted | UniProt_keyword | Yes | ||||
| secreted | secreted | UniProt_location | Yes | ||||
| secreted | secreted | HPA_secretome | Yes | ||||
| secreted | secreted | OmniPath | Yes | ||||
| glycoprotein | ecm | Matrisome | Yes | Yes |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Mass spectrometryMass spectrometry [LTQ-FT Ultra]Small R sequencing (Illumi HiSeq 2000 (Solexa) | 1 | 24196483 |
Sequence, Structure & Domains
Sequences
Length
891
Mass
96,060
Sequence
MLPTEVPQSHPGPSALLLLQLLLPPTSAFFPNIWSLLAAPGSITHQDLTEEAALNVTLQLFLEQPPPGRPPLRLEDFLGRTLLADDLFAAYFGPGSSRRFRAALGEVSRANAAQDFLPTSRNDPDLHFDAERLGQGRARLVGALRETVVAARALDHTLARQRLGAALHALQDFYSHSNWVELGEQQPHPHLLWPRQELQNLAQVADPTCSDCEELSCPRNWLGFTLLTSGYFGTHPPKPPGKCSHGGHFDRSSSQPPRGGINKDSTSPGFSPHHMLHLQAAKLALLASIQAFSLLRSRLGDRDFSRLLDITPASSLSFVLDTTGSMGEEINAAKIQARHLVEQRRGSPMEPVHYVLVPFHDPGFGPVFTTSDPDSFWQQLNEIHALGGGDEPEMCLSALQLALLHTPPLSDIFVFTDASPKDAFLTNQVESLTQERRCRVTFLVTEDTSRVQGRARREILSPLRFEPYKAVALASGGEVIFTKDQHIRDVAAIVGESMAALVTLPLDPPVVVPGQPLVFSVDGLLQKITVRIHGDISSFWIKNPAGVSQGQEEGGGPLGHTRRFGQFWMVTMDDPPQTGTWEIQVTAEDTPGVRVQAQTSLDFLFHFGIPMEDGPHPGLYPLTQPVAGLQTQLLVEVTGLGSRANPGDPQPHFSHVILRGVPEGAELGQVPLEPVGPPERGLLAASLSPTLLSTPRPFSLELIGQDAAGRRLHRAAPQPSTVVPVLLELSGPSGFLAPGSKVPLSLRIASFSGPQDLDLRTFVNPSFSLTSNLSRAHLELNESAWGRLWLEVPDSAAPDSVVMVTVTAGGREANPVPPTHAFLRLLVSAPAPQDRHTTPTGSSDPILTTATPAFSPFTLVTQGRAGAGLAAGSPWWGTVGGVLLLLGLASW
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9Y334-1; Sequence=Displayed; Name=2; IsoId=Q9Y334-2; Sequence=VSP_026494, VSP_026495
Alternative Sequence
834..860; DRHTTPTGSSDPILTTATPAFSPFTLV -> VRNHYFPSQGPAHHPYRLI (in isoform 2); 861..891; Missing (in isoform 2)
Domain & Motif Annotations
Domain (FT)
313..506; VWFA
Region
237..272; Disordered
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 37438638 | Extracellular Vesicles Play a Central Role in Cerebral Venous Disease-Associated Brain Atrophy. | No related sentences available |