Protein detail
PCDG9
Protocadherin gamma-A9 (PCDH-gamma-A9)
Protein symbol PCDG9 | UniProt ID | EVMP score 0.50 |
Frequency 3 | Transmembrane count 1 | Protein classification Predicted membrane proteins |
Basic Information
Protein Names
Protocadherin gamma-A9 (PCDH-gamma-A9)
Protein Class
Predicted membrane proteins
Transmembrane
693..713; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym
PCDH-GAMMA-A9
Gene Description
Protocadherin gamma subfamily A, 9
Chromosome
5
Position
141402778-141512975
Frequency
3
EVMP Score
0.50
Fluorescence & Localization
Tissue SpecificepididymisCell SpecificEpididymal principal cellsSingle-Nuclei Brain Specificchoroid plexus epithelial cellBlood Cell SpecificbasophilBlood Lineage Specificgranulocytes
Function & Pathway
Cellular Component
Biological Process
Mediation Categories
Adhesion and uptake mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
26 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| receptor | receptor | CellChatDB | No | Yes | No | Yes | No |
| receptor | receptor | OmniPath | No | Yes | No | Yes | No |
| extracellular | extracellular | OmniPath | No | No | No | Yes | No |
| intracellular | intracellular | ComPPI | No | No | No | Yes | No |
| intracellular | intracellular | OmniPath | No | No | No | Yes | No |
| cell_surface_ligand | cell_surface_ligand | CellChatDB | Yes | No | No | Yes | No |
| cell_surface_ligand | cell_surface_ligand | OmniPath | Yes | No | No | Yes | No |
| protocadherin | cell_adhesion | HGNC | Yes | Yes | No | Yes | No |
| adhesion | adhesion | HGNC | Yes | Yes | No | Yes | No |
| cell_adhesion | cell_adhesion | Zhong2015 | Yes | Yes | No | Yes | No |
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Regulatory Interaction Network
2 records.
| Source Protein Symbol | Source UniProt ID | Target Protein Symbol | Target UniProt ID | Is Directed | Is Stimulation | Is Inhibition | Database | References |
|---|---|---|---|---|---|---|---|---|
| PCDAA | Q9Y5I2 | PCDG9 | Q9Y5G4 | Yes | Yes | No | SIGNOR | SIGNOR:16697637 |
| PCDA2 | Q9Y5H9 | PCDG9 | Q9Y5G4 | Yes | Yes | No | SIGNOR | SIGNOR:16697637 |
Protein Complex Composition
0 records.
Sequence, Structure & Domains
Sequences
Length
932
Mass
101,687
Sequence
MAAPTKCQLRGRLVLLCSLLGMLWEARASQIRYSVPEETEKGYIVGNISKDLALEPRELAERRVRIVSRGRTQLFSLNPRSGTLVTAGRIDREELCAQSPRCLVNFKVLVEDRVKLYGIEIEVTDINDSAPKFQAESLEVKINEIAVPGARYPLPEAIDPDVGVNSLQSYQLSPNHHFSLNVQTGDNGAINPELVLERALDREEATAHHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAPVFAQRIYRVKVLENVPPGTWLLTATASDLDEGINGKVAYKFWKINEKQSLLFQLNENTGEISTAKSLDYEECSFYEMEIQAEDGGGLKGWTKVLISVEDVNDNRPEVTITSLFSPVREDAPQGTVILLFNAHDRDSGKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDRGTPPLSTEIHITLQVTDINDNPPAFSQASYSVYLPENNARGTSIFSVIAYDPDSNENSRVIYSLAEDTIQGSPLSTYVSINSDTGVLYALCSFDYEQFRDLQMQVTASDSGSPPLSSNVSLRLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLFKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAIADSIPDILADLGSLQIPADLEASDLTLYLVVAVAVVSCVFLTFVITLLALRLRHWHSSHLLRATSDGLAGVPTSHFVGVDGVRAFLQTYSQEFSLTADSRKSHLIFPQPNYADTLISQQSCEKNEPLCVSVDSKFPIEDTPLVPQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9Y5G4-1; Sequence=Displayed; Name=2; Synonyms=Short; IsoId=Q9Y5G4-2; Sequence=VSP_008675, VSP_008676
Alternative Sequence
809..828; QAPPNTDWRFSQAQRPGTSG -> VSSFFFFLSFLFLFFVLFCF (in isoform 2); 829..932; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Compositional Bias
816..841; Polar residues; 922..932; Basic residues
Domain (FT)
29..133; Cadherin 1; 134..242; Cadherin 2; 243..347; Cadherin 3; 348..452; Cadherin 4; 453..562; Cadherin 5; 570..683; Cadherin 6
Region
803..841; Disordered; 902..932; Disordered