Protein detail
CSAD
Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Aspartate 1-decarboxylase) (EC 4.1.1.11) (Cysteine-sulfinate decarboxylase) (Sulfinoalanine decarboxylase)
Entry name CSAD | UniProt ID | EVMP confidence score 0.38 |
Supporting publications (n) 1 | Transmembrane count | Protein classification EnzymesMetabolic proteinsPlasma proteinsPredicted intracellular proteins |
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40Basic Information11
Protein Names
Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Aspartate 1-decarboxylase) (EC 4.1.1.11) (Cysteine-sulfinate decarboxylase) (Sulfinoalanine decarboxylase)
Protein Class (4)
EnzymesMetabolic proteinsPlasma proteinsPredicted intracellular proteins
Protein Function (3)
- Enzymes
- Predicted intracellular proteins
- ENZYME proteins:Lyases
Ensembl
Entrez Gene Symbol
Gene Synonym (2)
CSDPCAP
Gene Description
Cysteine sulfinic acid decarboxylase
Chromosome
12
Position
53157663-53180925
Supporting publications (n)
1
EVMP confidence score
0.38
Fluorescence & Localization4
Tissue Specificblood vesselCell SpecificCardiomyocytesSingle-Nuclei Brain Specificvascular associated smooth muscle cell
Function & Pathway7
Protein Function (3)
- Enzymes
- Predicted intracellular proteins
- ENZYME proteins:Lyases
Cellular Component
Molecular Function (3)
Biological Process (3)
KEGG (4)
Reactome (3)
Mediation Categories
Metabolism mediation
Relations & Evidence5
Ligand-Receptor Signaling (3)
3 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Protein Complex Composition (1)
Isolation & Detection Technology (1)
Sequence, Structure & Domains11
Sequences
Length
493
Mass
55,023
Sequence
MADSEALPSLAGDPVAVEALLRAVFGVVVDEAIQKGTSVSQKVCEWKEPEELKQLLDLELRSQGESQKQILERCRAVIRYSVKTGHPRFFNQLFSGLDPHALAGRIITESLNTSQYTYEIAPVFVLMEEEVLRKLRALVGWSSGDGIFCPGGSISNMYAVNLARYQRYPDCKQRGLRTLPPLALFTSKECHYSIQKGAAFLGLGTDSVRVVKADERGKMVPEDLERQIGMAEAEGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWLHVDAAWGGSVLLSQTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHGSQASYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVEEMKKREGFELVMEPEFVNVCFWFVPPSLRGKQESPDYHERLSKVAPVLKERMVKEGSMMIGYQPHGTRGNFFRVVVANSALTCADMDFLLNELERLGQDL
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; Synonyms=Long; IsoId=Q9Y600-1; Sequence=Displayed; Name=2; Synonyms=Short; IsoId=Q9Y600-2; Sequence=VSP_001307; Name=3; IsoId=Q9Y600-3; Sequence=VSP_039002
Alternative Sequence
1; M -> MSIPLKSSFLLSYLCTLPPALLSREILM (in isoform 3); 43..189; Missing (in isoform 2)
3D Structural Models
Turn
32..34; 118..120; 248..250; 284..286
Helix
14..31; 35..37; 49..56; 67..80; 99..111; 122..139; 152..167; 171..174; 176..178; 193..200; 205..207; 221..233; 256..266; 277..282; 287..290; 293..295; 324..329; 345..347; 350..352; 362..396; 419..421; 430..435; 437..448; 476..490
Beta Strand
89..93; 145..151; 182..187; 208..211; 237..246; 269..274; 297..301; 314..319; 401..405; 408..416; 452..458; 461..468
3D Structure
X-ray crystallography (1)
Domain & Motif Annotations
Protein Families
Group II decarboxylase family
Sequence Similarities
Belongs to the group II decarboxylase family.
Supporting Publications1
| PMID | Title | Abstract |
|---|---|---|
| 32384937 | Alzheimer's disease progression characterized by alterations in the molecular profiles and biogenesis of brain extracellular vesicles. | No abstract available |