Protein detail
KPTN
KICSTOR complex protein kaptin (Actin-associated protein 2E4)
Protein symbol KPTN | UniProt ID | EVMP score 0.50 |
Frequency 5 | Transmembrane count | Protein classification Disease related genesHuman disease related genesPredicted intracellular proteins |
Basic Information
Protein Names
KICSTOR complex protein kaptin (Actin-associated protein 2E4)
Protein Class
Disease related genesHuman disease related genesPredicted intracellular proteins
Protein Function
- Disease related genes
- Human disease related genes:Other diseases:Mental and behavioural disorders
- Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
2E4KICS4
Gene Description
Kaptin, actin binding protein
Chromosome
19
Position
47475150-47484265
Frequency
5
EVMP Score
0.50
Fluorescence & Localization
Function & Pathway
Protein Function
- Disease related genes
- Human disease related genes:Other diseases:Mental and behavioural disorders
- Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Reactome
Mediation Categories
Fusion and delivery mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
4 records.
| Component Name | Component Gene Symbols | Component UniProt ID | Stoichiometry | Database | Database IDs | References |
|---|---|---|---|---|---|---|
| KICSTOR complex | ITFG2KICS2KPTNSZT2 | Q5T011Q969R8Q96MD2Q9Y664 | 1:1:1:1 | CORUMhu.MAPComplexPortal | intact:EBI-26361505CORUM:6754 | 2819930614755292 |
| ITFG2KICS2KPTNSZT2TMCO4 | Q5T011Q5TGY1Q969R8Q96MD2Q9Y664 | 0:0:0:0:0 | hu.MAPhu.MAP2 | |||
| ITFG2KICS2KPTNTMCO4 | Q5TGY1Q969R8Q96MD2Q9Y664 | 0:0:0:0 | hu.MAP | |||
| ITFG2KPTN | Q969R8Q9Y664 | 0:0 | hu.MAP2 |
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Mass spectrometry | 0 |
Sequence, Structure & Domains
Sequences
Length
436
Mass
48,080
Sequence
MMGEAAVAAGPCPLREDSFTRFSSQSNVYGLAGGAGGRGELLAATLKGKVLGFRYQDLRQKIRPVAKELQFNYIPVDAEIVSIDTFNKSPPKRGLVVGITFIKDSGDKGSPFLNIYCDYEPGSEYNLDSIAQSCLNLELQFTPFQLCHAEVQVGDQLETVFLLSGNDPAIHLYKENEGLHQFEEQPVENLFPELTNLTSSVLWLDVHNFPGTSRRLSALGCQSGYVRVAHVDQRSREVLQMWSVLQDGPISRVIVFSLSAAKETKDRPLQDEYSVLVASMLEPAVVYRDLLNRGLEDQLLLPGSDQFDSVLCSLVTDVDLDGRPEVLVATYGQELLCYKYRGPESGLPEAQHGFHLLWQRSFSSPLLAMAHVDLTGDGLQELAVVSLKGVHILQHSLIQASELVLTRLRHQVEQRRRRLQGLEDGAGAGPAENAAS
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9Y664-1; Sequence=Displayed; Name=2; IsoId=Q9Y664-2; Sequence=VSP_053990
Alternative Sequence
1..240; Missing (in isoform 2)