Browse EV MemProt Atlas
Supporting publications (n)

Number of publications supporting the inclusion of this protein in EV MemProt Atlas.

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
UniProt IDProtein namesProtein classificationTransmembrane countRelated DiseasesMediation categoriesDownload
AT1A2P50993Sodium/potassium-transporting ATPase subunit alpha-2 (Na(+)/K(+) ATPase alpha-2 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-2)Disease related genesEnzymesHuman disease related genes10Clinical-translation mediationFusion and delivery mediationMetabolism mediation0.38
AT2B2Q01814Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2)Disease related genesEnzymesFDA approved drug targets10Clinical-translation mediationFusion and delivery mediationImmune mediation0.38
ATP4AP20648Potassium-transporting ATPase alpha chain 1 (EC 7.2.2.19) (Gastric H(+)/K(+) ATPase subunit alpha) (Proton pump)EnzymesFDA approved drug targetsMetabolic proteins10Bacterial infectionCardiovascular diseaseColorectal cancerClinical-translation mediationFusion and delivery mediation0.38
B3ATP02730Band 3 anion transport protein (Anion exchange protein 1) (AE 1) (Anion exchanger 1) (Solute carrier family 4 member 1) (CD antigen CD233)Blood group antigen proteinsCD markersDisease related genes12Clinical-translation mediationFusion and delivery mediationImmune mediation0.38
CAD23Q9H251Cadherin-23 (Otocadherin)Disease related genesHuman disease related genesPredicted intracellular proteins1Adhesion and uptake mediationFusion and delivery mediationMetabolism mediation0.38
CFTRP13569Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)Cancer-related genesDisease related genesEnzymes12Bowel habit changeChronic obstructive pulmonary diseaseCystic fibrosisClinical-translation mediationFusion and delivery mediationMetabolism mediation0.38
CLD1O95832Claudin-1 (Senescence-associated epithelial membrane protein)Disease related genesHuman disease related genesPotential drug targets4Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation0.38
COPT1O15431High affinity copper uptake protein 1 (Copper transporter 1) (hCTR1) (Solute carrier family 31 member 1) [Cleaved into: Truncated CTR1 form]Metabolic proteinsPredicted membrane proteinsTransporters3Clinical-translation mediationFusion and delivery mediation0.38
CTL4Q53GD3Choline transporter-like protein 4 (Solute carrier family 44 member 4) (Thiamine pyrophosphate transporter 1) (hTPPT1)Disease related genesHuman disease related genesMetabolic proteins10Pancreatic cancerProstate cancerClinical-translation mediationFusion and delivery mediationMetabolism mediation0.38
CTNA2P26232Catenin alpha-2 (Alpha N-catenin) (Alpha-catenin-related protein)Disease related genesHuman disease related genesPlasma proteinsFusion and delivery mediation0.38
CUBNO60494Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor)Disease related genesHuman disease related genesMetabolic proteinsAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation0.38
CXB1P08034Gap junction beta-1 protein (Connexin-32) (Cx32) (GAP junction 28 kDa liver protein)Disease related genesHuman disease related genesPotential drug targets4Fusion and delivery mediation0.38
DMDP11532DystrophinCancer-related genesDisease related genesFDA approved drug targetsCystic fibrosisEpilepsy/seizureEye anterior segment structural developmental anomalyClinical-translation mediationFusion and delivery mediationMetabolism mediation0.38
DPP4P27487Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)]CD markersEnzymesFDA approved drug targets1Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation0.38
DSG1Q02413Desmoglein-1 (Cadherin family member 4) (Desmosomal glycoprotein 1) (DG1) (DGI) (Pemphigus foliaceus antigen)Disease related genesHuman disease related genesPlasma proteins1Adhesion and uptake mediationFusion and delivery mediationImmune mediation0.38
DUSTYQ6XUX3Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) (Receptor-interacting serine/threonine-protein kinase 5) (Sugen kinase 496) (SgK496)Disease related genesEnzymesHuman disease related genesFusion and delivery mediationReceptor-signaling mediation0.38
EAA3P43005Excitatory amino acid transporter 3 (Excitatory amino-acid carrier 1) (Neuronal and epithelial glutamate transporter) (Sodium-dependent glutamate/aspartate transporter 3) (Solute carrier family 1 member 1)Disease related genesHuman disease related genesMetabolic proteins8Clinical-translation mediationFusion and delivery mediationImmune mediation0.38
FCERGP30273High affinity immunoglobulin epsilon receptor subunit gamma (Fc receptor gamma-chain) (FcRgamma) (Fc-epsilon RI-gamma) (IgE Fc receptor subunit gamma) (FceRI gamma)FDA approved drug targetsPredicted membrane proteins1Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation0.38
GNA11P29992Guanine nucleotide-binding protein subunit alpha-11 (G alpha-11) (G-protein subunit alpha-11) (EC 3.6.5.-) (Guanine nucleotide-binding protein G(y) subunit alpha)Cancer-related genesDisease related genesHuman disease related genesFusion and delivery mediationImmune mediationMetabolism mediation0.38
GNAOP09471Guanine nucleotide-binding protein G(o) subunit alpha (EC 3.6.5.-)Disease related genesHuman disease related genesPredicted intracellular proteinsFusion and delivery mediationReceptor-signaling mediation0.38
IDEP14735Insulin-degrading enzyme (EC 3.4.24.56) (Abeta-degrading protease) (Insulin protease) (Insulinase) (Insulysin)EnzymesFDA approved drug targetsPlasma proteinsInherited retinal dystrophySkin and skin-structure infectionClinical-translation mediationFusion and delivery mediationImmune mediation0.38
IPSPP05154Plasma serine protease inhibitor (Acrosomal serine protease inhibitor) (Plasminogen activator inhibitor 3) (PAI-3) (PAI3) (Protein C inhibitor) (PCI) (Serpin A5)Cancer-related genesCandidate cardiovascular disease genesPlasma proteinsCOVID-19Clinical-translation mediationFusion and delivery mediationImmune mediation0.38
ITA2P17301Integrin alpha-2 (CD49 antigen-like family member B) (Collagen receptor) (Platelet membrane glycoprotein Ia) (GPIa) (VLA-2 subunit alpha) (CD antigen CD49b)Cancer-related genesCD markersHuman disease related genes1Colorectal cancerSolid tumour/cancerAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation0.38
KCMA1Q12791Calcium-activated potassium channel subunit alpha-1 (BK channel) (BKCA alpha) (Calcium-activated potassium channel, subfamily M subunit alpha-1) (K(VCA)alpha) (KCa1.1) (Maxi K channel) (MaxiK) (Slo-alpha) (Slo1) (Slowpoke homolog) (Slo homolog) (hSlo)Disease related genesFDA approved drug targetsHuman disease related genes7AsthmaFunctional bladder disorderClinical-translation mediationFusion and delivery mediationImmune mediation0.38
LRP6O75581Low-density lipoprotein receptor-related protein 6 (LRP-6)Cancer-related genesDisease related genesHuman disease related genes1Clinical-translation mediationFusion and delivery mediationReceptor-signaling mediation0.38

626-650 of 792 proteins

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