Protein detail
UPK2
Uroplakin-2 (UP2) (Uroplakin II) (UPII)
Protein symbol UPK2 | UniProt ID | EVMP score 0.38 |
Frequency | Transmembrane count 1 | Protein classification Predicted membrane proteinsTransporters |
Basic Information
Protein Names
Uroplakin-2 (UP2) (Uroplakin II) (UPII)
Protein Class
Predicted membrane proteinsTransporters
Protein Function
Transporters:Accessory Factors Involved in Transport
Transmembrane
156..176; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym
MGC138598UP2UPII
Gene Description
Uroplakin 2
Chromosome
11
Position
118925164-118958559
EVMP Score
0.38
Fluorescence & Localization
Tissue SpecificbrainBrain Regional SpecificcerebellumCell SpecificBrain excitatory neurons
Function & Pathway
Protein Function
Transporters:Accessory Factors Involved in Transport
Cellular Component
Molecular Function
Biological Process
Canonical Pathways
M177 Pid epha fwdpathway
Mediation Categories
Fusion and delivery mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
16 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transmembrane | transmembrane | UniProt_location | No | No | No | Yes | No |
| transmembrane | transmembrane | UniProt_topology | No | No | No | Yes | No |
| transmembrane | transmembrane | UniProt_keyword | No | No | No | Yes | No |
| transmembrane_predicted | transmembrane | OmniPath | No | No | No | Yes | No |
| transmembrane | transmembrane | Ramilowski_location | No | No | No | Yes | No |
| transmembrane | transmembrane | OmniPath | No | No | No | Yes | No |
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | Yes | No |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | Yes | No |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | Membranome | No | No | No | Yes | No |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | OmniPath | No | No | No | Yes | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
Sequence, Structure & Domains
Sequences
Length
184
Mass
19,438
Sequence
MAPLLPIRTLPLILILLALLSPGAADFNISSLSGLLSPALTESLLVALPPCHLTGGNATLMVRRANDSKVVTSSFVVPPCRGRRELVSVVDSGAGFTVTRLSAYQVTNLVPGTKFYISYLVKKGTATESSREIPMSTLPRRNMESIGLGMARTGGMVVITVLLSVAMFLLVLGFIIALALGSRK
3D Structural Models
Domain & Motif Annotations
Protein Families
Uroplakin-2 family
Sequence Similarities
Belongs to the uroplakin-2 family.