Protein detail
UPK2
Uroplakin-2 (UP2) (Uroplakin II) (UPII)
Entry name UPK2 | UniProt ID | EVMP confidence score 0.23 |
Supporting publications (n) 0 | Transmembrane count 1 | Protein classification Predicted membrane proteinsTransporters |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Uroplakin-2 (UP2) (Uroplakin II) (UPII)
Protein Class (2)
Predicted membrane proteinsTransporters
Protein Function
Transporters:Accessory Factors Involved in Transport
Transmembrane
156..176; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym (3)
MGC138598UP2UPII
Gene Description
Uroplakin 2
Chromosome
11
Position
118925164-118958559
Supporting publications (n)
0
EVMP confidence score
0.23
Fluorescence & Localization
Tissue SpecificbrainBrain Regional SpecificcerebellumCell SpecificBrain excitatory neurons
Function & Pathway
Protein Function
Transporters:Accessory Factors Involved in Transport
Cellular Component (3)
Molecular Function
Biological Process (3)
Canonical Pathways
M177 Pid epha fwdpathway
Mediation Categories
Fusion and delivery mediation
Relations & Evidence17
Ligand-Receptor Signaling (16)
16 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transmembrane | transmembrane | UniProt_location | Yes | ||||
| transmembrane | transmembrane | UniProt_topology | Yes | ||||
| transmembrane | transmembrane | UniProt_keyword | Yes | ||||
| transmembrane_predicted | transmembrane | OmniPath | Yes | ||||
| transmembrane | transmembrane | Ramilowski_location | Yes | ||||
| transmembrane | transmembrane | OmniPath | Yes | ||||
| plasma_membrane | plasma_membrane | UniProt_location | Yes | ||||
| plasma_membrane | plasma_membrane | OmniPath | Yes | ||||
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | Membranome | Yes | ||||
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | OmniPath | Yes |
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Isolation & Detection Technology (1)
Sequence, Structure & Domains
Sequences
Length
184
Mass
19,438
Sequence
MAPLLPIRTLPLILILLALLSPGAADFNISSLSGLLSPALTESLLVALPPCHLTGGNATLMVRRANDSKVVTSSFVVPPCRGRRELVSVVDSGAGFTVTRLSAYQVTNLVPGTKFYISYLVKKGTATESSREIPMSTLPRRNMESIGLGMARTGGMVVITVLLSVAMFLLVLGFIIALALGSRK
Domain & Motif Annotations
Protein Families
Uroplakin-2 family
Sequence Similarities
Belongs to the uroplakin-2 family.