Protein detail
UPK2
Uroplakin-2 (UP2) (Uroplakin II) (UPII)
Entry name UPK2 | UniProt ID | EVMP confidence score 0.38 |
Supporting publications (n) | Transmembrane count 1 | Protein classification Predicted membrane proteinsTransporters |
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40Basic Information12
Protein Names
Uroplakin-2 (UP2) (Uroplakin II) (UPII)
Protein Class (2)
Predicted membrane proteinsTransporters
Protein Function
Transporters:Accessory Factors Involved in Transport
Transmembrane
156..176; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym (3)
MGC138598UP2UPII
Gene Description
Uroplakin 2
Chromosome
11
Position
118925164-118958559
EVMP confidence score
0.38
Fluorescence & Localization3
Tissue SpecificbrainBrain Regional SpecificcerebellumCell SpecificBrain excitatory neurons
Function & Pathway6
Protein Function
Transporters:Accessory Factors Involved in Transport
Cellular Component (3)
Molecular Function
Biological Process (3)
Canonical Pathways
M177 Pid epha fwdpathway
Mediation Categories
Fusion and delivery mediation
Relations & Evidence17
Ligand-Receptor Signaling (16)
16 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| cell_surface | cell_surface | Surfaceome | No | No | No | Yes | No |
| cell_surface | cell_surface | OmniPath | No | No | No | Yes | No |
| transmembrane | transmembrane_predicted | Phobius | No | No | No | Yes | No |
| transmembrane_phobius | transmembrane_predicted | Almen2009 | No | No | No | Yes | No |
| transmembrane_sosui | transmembrane_predicted | Almen2009 | No | No | No | Yes | No |
| transmembrane_tmhmm | transmembrane_predicted | Almen2009 | No | No | No | Yes | No |
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Isolation & Detection Technology (1)
Sequence, Structure & Domains5
Sequences
Length
184
Mass
19,438
Sequence
MAPLLPIRTLPLILILLALLSPGAADFNISSLSGLLSPALTESLLVALPPCHLTGGNATLMVRRANDSKVVTSSFVVPPCRGRRELVSVVDSGAGFTVTRLSAYQVTNLVPGTKFYISYLVKKGTATESSREIPMSTLPRRNMESIGLGMARTGGMVVITVLLSVAMFLLVLGFIIALALGSRK
Domain & Motif Annotations
Protein Families
Uroplakin-2 family
Sequence Similarities
Belongs to the uroplakin-2 family.