Protein detail

TSN4

Tetraspanin-4 (Tspan-4) (Novel antigen 2) (NAG-2) (Transmembrane 4 superfamily member 7)

Protein symbol
TSN4
UniProt ID
O14817
EVMP score
0.25
Frequency
3
Transmembrane count
4
Protein classification
Basic Information
Protein Names
Tetraspanin-4 (Tspan-4) (Novel antigen 2) (NAG-2) (Transmembrane 4 superfamily member 7)
Transmembrane
14..34; Helical; 56..76; Helical; 86..106; Helical; 202..222; Helical
Transmembrane Count
4
Ensembl
ENSG00000214063
Entrez Gene Symbol
TSPAN4
Frequency
3
EVMP Score
0.25
Fluorescence & Localization
Cell SpecificEsophageal basal cells
Function & Pathway
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Adhesion and uptake mediation
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

22 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
receptorreceptorCellCellInteractionsNoYesNoYesNo
transmembranetransmembrane_predictedPhobiusNoNoNoYesNo
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Regulatory Interaction Network

0 records.

Protein Complex Composition

0 records.

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Fetch_ErrorMass spectrometrySmall R sequencing (Illumi HiSeq 2000 (Solexa)R Sequencing23743030739015940
Sequence, Structure & Domains

Sequences

Length
238
Mass
26,118
Sequence
MARACLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCCLEFSESCGLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVKADTYCA

3D Structural Models

Domain & Motif Annotations

Protein Families
Tetraspanin (TM4SF) family
Sequence Similarities
Belongs to the tetraspanin (TM4SF) family.
Clinical Relevance