Protein detail
PSCA
Prostate stem cell antigen
Protein symbol PSCA | UniProt ID | EVMP score 0.50 |
Frequency 2 | Transmembrane count | Protein classification Cancer-related genesPredicted intracellular proteinsPredicted membrane proteins |
Basic Information
Protein Names
Prostate stem cell antigen
Protein Class
Cancer-related genesPredicted intracellular proteinsPredicted membrane proteins
Protein Function
- Cancer-related genes:Candidate cancer biomarkers
- Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
lncPSCA
Gene Description
Prostate stem cell antigen
Chromosome
8
Position
142670308-142682725
Frequency
2
EVMP Score
0.50
Fluorescence & Localization
Cell SpecificCytotrophoblastsSingle-Nuclei Brain Specificendothelial cellBlood Cell Specificclassical monocyte
Function & Pathway
Protein Function
- Cancer-related genes:Candidate cancer biomarkers
- Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Reactome
Canonical Pathways
- M46 Pid atr pathway
- M70 Pid ps1 pathway
- M129 Pid plk1 pathway
Mediation Categories
Clinical-translation mediationMetabolism mediationReceptor-signaling mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
15 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| ecm | ecm | MatrixDB | Yes | No | No | No | No |
| ecm | ecm | OmniPath | Yes | No | No | No | No |
| intracellular | intracellular | LOCATE | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
| ly6_plaur | receptor_regulator | OmniPath | Yes | No | No | No | No |
| receptor_regulator | receptor_regulator | OmniPath | Yes | No | No | No | No |
| transmembrane | transmembrane | GO_Intercell | No | No | No | No | No |
| transmembrane | transmembrane | LOCATE | No | No | No | No | No |
| transmembrane | transmembrane | Ramilowski_location | No | No | No | No | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Sequence, Structure & Domains
Sequences
Length
114
Mass
11,959
Sequence
MAGLALQPGTALLCYSCKAQVSNEDCLQVENCTQLGEQCWTARIRAVGLLTVISKGCSLNCVDDSQDYYVGKKNITCCDTDLCNASGAHALQPAAAILALLPALGLLLWGPGQL
3D Structural Models
Domain & Motif Annotations
Domain (FT)
12..98; UPAR/Ly6
Clinical Relevance
Disease Involvement
Cancer-related genes
Related Diseases
Biomarker
Phase 1; Phase 2; Phase 1/2
Drugs