Protein detail
VAMP5
Vesicle-associated membrane protein 5 (VAMP-5) (Myobrevin)
Entry name VAMP5 | UniProt ID | EVMP score 0.50 |
Frequency 1 | Transmembrane count 1 | Protein classification Predicted membrane proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Vesicle-associated membrane protein 5 (VAMP-5) (Myobrevin)
Protein Class
Predicted membrane proteins
Transmembrane
73..93; Helical; Anchor for type IV membrane protein
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Description
Vesicle associated membrane protein 5
Chromosome
2
Position
85584431-85593406
Frequency
1
EVMP Score
0.50
Fluorescence & Localization
Cell SpecificLate spermatids
Function & Pathway
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Fusion and delivery mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
19 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transmembrane | transmembrane | OmniPath | No | No | No | Yes | No |
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | Yes | No |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | Yes | No |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | CSPA | No | No | No | Yes | No |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | OmniPath | No | No | No | Yes | No |
| transmembrane | transmembrane_predicted | Phobius | No | No | No | Yes | No |
| transmembrane_phobius | transmembrane_predicted | Almen2009 | No | No | No | Yes | No |
| transmembrane_sosui | transmembrane_predicted | Almen2009 | No | No | No | Yes | No |
| transmembrane_tmhmm | transmembrane_predicted | Almen2009 | No | No | No | Yes | No |
Page 2 of 2Previous
Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Mass spectrometry | 1 | 32002171 |
Sequence, Structure & Domains
Sequences
Length
116
Mass
12,805
Sequence
MAGIELERCQQQANEVTEIMRNNFGKVLERGVKLAELQQRSDQLLDMSSTFNKTTQNLAQKKCWENIRYRICVGLVVVGVLLIILIVLLVVFLPQSSDSSSAPRTQDAGIASGPGN
3D Structural Models
Domain & Motif Annotations
Domain (FT)
5..65; v-SNARE coiled-coil homology
Region
96..116; Disordered
Protein Families
Synaptobrevin family
Sequence Similarities
Belongs to the synaptobrevin family.
Clinical Relevance
Antibody
Interaction Protein
ENSG00000053501ENSG00000086827ENSG00000092108ENSG00000099940ENSG00000103496ENSG00000104915ENSG00000105402ENSG00000106089ENSG00000108587ENSG00000108679ENSG00000117758ENSG00000124207ENSG00000124222ENSG00000125991ENSG00000134265ENSG00000135249ENSG00000135823ENSG00000136631ENSG00000136874ENSG00000162236ENSG00000164294ENSG00000170310ENSG00000177951
Interaction Count
23
Interaction Dataset
biogrid_bioplexintact_biogrid_bioplexintact_biogrid